University of Houston College of Optometry, Houston, Texas.
Optom Vis Sci. 2020 Sep;97(9):754-760. doi: 10.1097/OPX.0000000000001564.
An equivalent 12 months of cleaning did not induce significant changes in the optical aberrations or base curves of scleral lenses.
This study aimed to test whether an equivalent of 12 months of manual cleaning alters the optical and physical properties of conventional and wavefront-guided scleral lenses.
Twelve scleral lenses (four repeats of three designs, termed A, B, and C) were manufactured in Boston XO material: design A, -5.00 D defocus; design B, -5.00 D defocus with -0.153-μm vertical coma; and design C, -5.00 D defocus with a full custom wavefront-guided correction (second to fifth Zernike radial orders) of an eye with severe keratoconus. One lens of each design group served as a control and was not cleaned. To simulate a year of cleaning, seven individuals cleaned nine lenses (three from each group) twice a day for 27 days using the palm technique and commercially available cleaners, resulting in 378 cleanings of each lens. Lens aberrations were optically profiled and base curve radii were measured at baseline and after every 42nd cleaning. Differences in higher-order root mean square (HORMS) wavefront error and base curve radii associated with cleaning were compared with clinical benchmarks and using sign tests.
For the experimental lenses, median change in Seidel spherical dioptric power was +0.01 D (maximum, +0.025 D). Median change in HORMS wavefront error was 0.013 μm (maximum, 0.019 μm). All lenses exhibited HORMS changes less than one-eighth equivalent diopters (P = .002). Median percentage change in HORMS wavefront error in the three wavefront-guided lenses was 0.96% (maximum, 1.25%). Median change in base curve radii was 0.00 mm, with all lenses exhibiting changes (P = .002), less than the American National Standards Institute tolerance of 0.05 mm.
Cleaning over an equivalent 12-month period did not induce clinically significant changes in the optical or base curve properties of conventional or wavefront-guided scleral lenses.
12 个月的等效清洁并未引起巩膜镜片的像差或基底曲线发生显著变化。
本研究旨在测试等效 12 个月的手动清洁是否会改变传统和波前引导巩膜镜片的光学和物理特性。
使用 Boston XO 材料制造了 12 个巩膜镜片（三个设计的四个重复，分别称为 A、B 和 C）：设计 A，-5.00 D 远视离焦；设计 B，-5.00 D 远视离焦，带有-0.153μm 垂直彗差；设计 C，-5.00 D 远视离焦，具有严重圆锥角膜的眼睛的全定制波前引导矫正（第二至第五 Zernike 径向阶数）。每个设计组的一个镜片作为对照，不进行清洁。为了模拟一年的清洁，七个人每天使用手掌技术和市售清洁剂清洁九只镜片（每组三只）两次，每只镜片清洁 378 次，共清洁 378 次。在基线和每次第 42 次清洁后，通过光学轮廓仪测量镜片像差，并测量基底曲线半径。使用符号检验比较与清洁相关的高阶均方根（HORMS）波前误差和基底曲线半径的差异，并与临床基准进行比较。
对于实验镜片，Seidel 球镜屈光力的中位数变化为+0.01 D（最大，+0.025 D）。HORMS 波前误差的中位数变化为 0.013 μm（最大，0.019 μm）。所有镜片的 HORMS 变化均小于八分之一等效屈光度（P =.002）。三个波前引导镜片的 HORMS 波前误差中位数变化率为 0.96%（最大，1.25%）。基底曲线半径的中位数变化为 0.00 mm，所有镜片均发生变化（P =.002），小于美国国家标准协会 0.05 mm 的公差。
在等效 12 个月的清洁期间，传统或波前引导巩膜镜片的光学或基底曲线特性未发生临床显著变化。
