Goyal Amrita, Jacobsen Audrey A, O'Leary Daniel, Watson Allison, Luikart Sharon, Gaddis Kevin J
Department of Dermatology, University of Minnesota, Minneapolis, MN.
Dermatol Online J. 2020 Aug 15;26(8):13030/qt1v33j40c.
A 61-year-old man with metastatic renal cell carcinoma on cabozantinib developed hand-foot skin reaction with predominantly dorsal involvement including painful violaceous plaques over the joints and keratotic yellow plaques on the palmar fingers. The medication was discontinued with resolution of the plaques and later reinitiated at a lower dose uneventfully.
一名61岁的转移性肾细胞癌男性患者正在接受卡博替尼治疗,出现了手足皮肤反应,主要累及背部,包括关节处疼痛的紫红色斑块以及手掌手指上的角化性黄色斑块。停用该药物后斑块消退,之后以较低剂量重新开始用药,过程顺利。