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[猴实验性牙周炎期间白细胞活性的评估]

[Evaluation of the activity of leukocytes during experimental periodontitis in the monkey].

作者信息

Gagnot G, Michel J F, Legall E, Merdrignac G, Genetet B

机构信息

Faculté de Chirurgie Dentaire, Rennes.

出版信息

J Biol Buccale. 1988 Mar;16(1):25-30.

PMID:3294233
Abstract

Polymorphonuclear leucocytes play an important role in the defense mechanisms and destruction of periodontal tissues. The leucocytes number and activity were compared during an induced periodontitis in 3 Cercopithecus cephus. On day 0, the 3 animals presented a localized marginal gingivitis. On 2 animals a severe marginal periodontitis was induced unilaterally: 42 days later leucocytes were sampled in the peripheral blood, in the gingival blood and in the gingival sulcus on the experimental and control sites as well as on the 2 hemijaws of the control animal. For each sample, a leucocyte count and a chemiluminescence test were done. Different results related to the disease severity were obtained with these tests for gingival blood and sulcular fluid.

摘要

多形核白细胞在牙周组织的防御机制和破坏过程中发挥着重要作用。在3只白顶白眉猴诱发牙周炎期间,对白细胞数量和活性进行了比较。在第0天,3只动物均表现为局限性边缘性牙龈炎。对其中2只动物单侧诱发严重边缘性牙周炎:42天后,在实验部位和对照部位的外周血、牙龈血和龈沟以及对照动物的两半颌骨采集白细胞样本。对每个样本进行白细胞计数和化学发光试验。通过这些试验,在牙龈血和龈沟液方面获得了与疾病严重程度相关的不同结果。

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