Al Habash Ahmed, Alrushoud Muath, Al Abdulsalam Omar, Al Somali Abdulaziz Ismail, Aljindan Mohanna, Al Ahmadi Adel Salah
Department of Ophthalmology, College of Medicine, King Fahd Hospital of the University, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia.
Eye Specialist Hospital, Ministry of Health, Dhahran, Saudi Arabia.
Clin Ophthalmol. 2020 Aug 25;14:2491-2496. doi: 10.2147/OPTH.S267303. eCollection 2020.
To report the surgical outcomes of combined gonioscopy-assisted transluminal trabeculotomy (GATT) with ab interno canaloplasty (ABiC) in conjunction with phacoemulsification for primary open-angle glaucoma (POAG).
This prospective, interventional, non-comparative case series included POAG patients who underwent combined GATT and ABiC in conjunction with phacoemulsification performed between January 2018 and August 2018. Main outcome measures include surgical success rate, changes in intraocular pressure (IOP), number of antiglaucoma medications, corrected distance visual acuity (CDVA), and complications.
We enrolled twenty eyes of 19 patients in our study. The mean age was 61.2 ± 6 years, and all the patients completed a 12-month follow-up. The overall success rate was 100%. The mean baseline IOP was 19.75 ± 4.68 mmHg, and at 12 months, the mean IOP was 13.30 ± 1.30 mmHg (IOP reduction of 32.7%). The baseline number of antiglaucoma medications was 3.4 ± 0.6 (range: 2 to 4 medications), and after 12 months follow-up, the number was reduced to 1.1 ± 1.0 (range: 0 to 2 medications). The CDVA for all 20 eyes was 0.85±0.58 LogMAR at baseline, and 0.16±0.30 LogMAR at 12-month follow-up. Only six eyes developed hyphaema, which had cleared by the first postoperative month, and three eyes needed medical treatment for postoperative IOP spikes.
The 12-month results of our study suggest that combined GATT with ABiC in conjunction with phacoemulsification is a safe and effective alternative in decreasing the IOP and number of antiglaucoma medications in POAG patients.
报告原发性开角型青光眼（POAG）患者联合房角镜辅助小梁切开术（GATT）与内路小梁成形术（ABiC）并联合白内障超声乳化术的手术效果。
本前瞻性、干预性、非对照病例系列研究纳入了2018年1月至2018年8月期间接受GATT联合ABiC并联合白内障超声乳化术的POAG患者。主要观察指标包括手术成功率、眼压（IOP）变化、抗青光眼药物数量、矫正远视力（CDVA）及并发症。
本研究共纳入19例患者的20只眼。平均年龄为61.2±6岁，所有患者均完成了12个月的随访。总体成功率为100%。基线平均IOP为19.75±4.68 mmHg，12个月时平均IOP为13.30±1.30 mmHg（IOP降低32.7%）。基线抗青光眼药物数量为3.4±0.6（范围：2至4种药物），随访12个月后，数量减少至1.1±1.0（范围：0至2种药物）。所有20只眼的基线CDVA为0.85±0.58 LogMAR，12个月随访时为0.16±0.30 LogMAR。仅6只眼出现前房积血，术后第1个月已清除，3只眼因术后IOP峰值需要药物治疗。
本研究12个月的结果表明，GATT联合ABiC并联合白内障超声乳化术是降低POAG患者IOP及抗青光眼药物数量的一种安全有效的替代方法。
