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Lung Cancer. 2019 Oct;136:6-14. doi: 10.1016/j.lungcan.2019.08.001. Epub 2019 Aug 2.

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Society for Translational Medicine consensus on postoperative management of EGFR-mutant lung cancer (2019 edition).转化医学学会关于表皮生长因子受体(EGFR)突变型肺癌术后管理的共识(2019年版)
Transl Lung Cancer Res. 2019 Dec;8(6):1163-1173. doi: 10.21037/tlcr.2019.12.14.
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Overall Survival with Osimertinib in Untreated, -Mutated Advanced NSCLC.奥希替尼治疗未经治、-突变型晚期 NSCLC 的总生存期。
N Engl J Med. 2020 Jan 2;382(1):41-50. doi: 10.1056/NEJMoa1913662. Epub 2019 Nov 21.
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A meta-analysis of adjuvant EGFR-TKIs for patients with resected non-small cell lung cancer.辅助 EGFR-TKIs 治疗可切除非小细胞肺癌的荟萃分析。
Lung Cancer. 2019 Nov;137:7-13. doi: 10.1016/j.lungcan.2019.08.002. Epub 2019 Aug 5.
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The Unique Spatial-Temporal Treatment Failure Patterns of Adjuvant Gefitinib Therapy: A Post Hoc Analysis of the ADJUVANT Trial (CTONG 1104).辅助吉非替尼治疗的独特时空治疗失败模式:ADJUVANT 试验(CTONG 1104)的事后分析。
J Thorac Oncol. 2019 Mar;14(3):503-512. doi: 10.1016/j.jtho.2018.11.020. Epub 2018 Dec 3.
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Erlotinib versus vinorelbine plus cisplatin as adjuvant therapy in Chinese patients with stage IIIA EGFR mutation-positive non-small-cell lung cancer (EVAN): a randomised, open-label, phase 2 trial.厄洛替尼对比长春瑞滨联合顺铂用于表皮生长因子受体突变阳性的 IIIA 期非小细胞肺癌中国患者的辅助治疗(EVAN):一项随机、开放标签、二期临床试验。
Lancet Respir Med. 2018 Nov;6(11):863-873. doi: 10.1016/S2213-2600(18)30277-7. Epub 2018 Aug 24.
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Assessment of Resistance Mechanisms and Clinical Implications in Patients With EGFR T790M-Positive Lung Cancer and Acquired Resistance to Osimertinib.评估 EGFR T790M 阳性肺癌患者对奥希替尼获得性耐药的耐药机制及临床意义。
JAMA Oncol. 2018 Nov 1;4(11):1527-1534. doi: 10.1001/jamaoncol.2018.2969.
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Frequency of the acquired resistant mutation T790 M in non-small cell lung cancer patients with active exon 19Del and exon 21 L858R: a systematic review and meta-analysis.伴有活跃的外显子 19Del 和外显子 21 L858R 的非小细胞肺癌患者中获得性耐药突变 T790M 的频率:系统评价和荟萃分析。
BMC Cancer. 2018 Feb 6;18(1):148. doi: 10.1186/s12885-018-4075-5.
8
Gefitinib versus vinorelbine plus cisplatin as adjuvant treatment for stage II-IIIA (N1-N2) EGFR-mutant NSCLC (ADJUVANT/CTONG1104): a randomised, open-label, phase 3 study.吉非替尼对比长春瑞滨联合顺铂作为 EGFR 突变型 II-IIIA 期(N1-N2)可切除 NSCLC(ADJUVANT/CTONG1104)的辅助治疗:一项随机、开放标签、III 期研究。
Lancet Oncol. 2018 Jan;19(1):139-148. doi: 10.1016/S1470-2045(17)30729-5. Epub 2017 Nov 21.
9
Osimertinib in Untreated EGFR-Mutated Advanced Non-Small-Cell Lung Cancer.奥希替尼治疗未经治疗的 EGFR 突变型晚期非小细胞肺癌。
N Engl J Med. 2018 Jan 11;378(2):113-125. doi: 10.1056/NEJMoa1713137. Epub 2017 Nov 18.
10
Osimertinib As First-Line Treatment of EGFR Mutation-Positive Advanced Non-Small-Cell Lung Cancer.奥希替尼作为 EGFR 突变阳性晚期非小细胞肺癌的一线治疗药物。
J Clin Oncol. 2018 Mar 20;36(9):841-849. doi: 10.1200/JCO.2017.74.7576. Epub 2017 Aug 25.

Postoperative management for non-small cell lung cancer harboring mutations.

作者信息

Tanaka Fumihiro, Yoneda Kazue, Takenaka Masaru

机构信息

Second Department of Surgery (Chest Surgery), University of Occupational and Environmental Health, Japan, Iseigaoka 1-1, Yahata-nishi-ku, Kitakyushu 807-8555 Japan.

出版信息

J Thorac Dis. 2020 Aug;12(8):4556-4560. doi: 10.21037/jtd-2020-45.

DOI:10.21037/jtd-2020-45
PMID:32944374
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7475602/
Abstract
摘要