Ito Takanori, Fujita Kohei, Okamura Misato, Okuno Yoshiaki, Saito Zentaro, Kanai Osamu, Nakatani Koichi, Moriyoshi Koki, Mio Tadashi
Division of Respiratory Medicine, Center of Respiratory Diseases, National Hospital Organization Kyoto Medical Center, Kyoto, Japan.
Department of Haematology, National Hospital Organization Kyoto Medical Center, Kyoto, Japan.
Respir Med Case Rep. 2020 Aug 28;31:101206. doi: 10.1016/j.rmcr.2020.101206. eCollection 2020.
Diffuse large B-cell lymphoma (DLBCL) is a common cancer in haematology. We report a case of DLBCL mimicking malignant pleural mesothelioma (MPM). A 75-year-old man with a 1-week exacerbation of dyspnoea on exertion and right pleural effusion on chest radiography was admitted to our hospital. Positron emission tomography/computed tomography revealed diffuse pleural thick lesions and massive pleural effusion, and these lesions had accumulation of fluorodeoxyglucose. Because we suspected MPM or lung cancer, we performed a biopsy with thoracoscopy to confirm the diagnosis. A biopsy of the pleural effusion with thoracoscopy revealed DLBCL. Chemotherapy was immediately selected, and the diffuse thickened pleural wall and massive pleural effusion of the right chest were significantly improved after two cycles of chemotherapy.
弥漫性大B细胞淋巴瘤（DLBCL）是血液学中一种常见的癌症。我们报告一例误诊为恶性胸膜间皮瘤（MPM）的DLBCL病例。一名75岁男性，因劳力性呼吸困难加重1周且胸部X线检查发现右侧胸腔积液入院。正电子发射断层扫描/计算机断层扫描显示弥漫性胸膜增厚病变及大量胸腔积液，这些病变有氟脱氧葡萄糖聚集。由于我们怀疑是MPM或肺癌，遂行胸腔镜活检以明确诊断。胸腔镜下对胸腔积液进行活检显示为DLBCL。随即选择化疗，两个周期化疗后，右侧胸部弥漫增厚的胸膜壁及大量胸腔积液明显改善。
