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房颤术后早期房性快速性心律失常复发的发生率及临床影响。

Incidence and clinical impact of early recurrence of atrial tachyarrhythmia after surgical ablation for atrial fibrillation.

机构信息

Division of Cardiology, Pusan National University, School of Medicine, Pusan National University Yangsan Hospital, Yangsan, Republic of Korea.

Department of Cardiovascular and Thoracic Surgery, Pusan National University, School of Medicine, Pusan National University Yangsan Hospital, Yangsan, Republic of Korea.

出版信息

J Cardiovasc Electrophysiol. 2020 Nov;31(11):2898-2906. doi: 10.1111/jce.14749. Epub 2020 Oct 1.

Abstract

BACKGROUND

Atrial tachyarrhythmias (ATAs) are common within the 3-month blanking period after catheter ablation of atrial fibrillation (AF). However, little evidence is available regarding the current guidelines on the blanking period after surgical AF ablation. We investigate the incidence and significance of early recurrence of atrial tachyarrhythmia (ERAT) and evaluate the optimal blanking period after surgical AF ablation.

METHODS

Data from 259 patients who underwent surgical AF ablation from 2009 to 2016 were collected. ERAT was defined as documented ATA episodes lasting for 30 s. A multivariate Cox proportional hazard model was constructed to evaluate the role of ERAT as a predictor of late recurrences (LR) for AF.

RESULTS

In total, 127 patients (49.0%) experienced their last episodes of ERAT during the first (n = 65), second (n = 14), or third (n = 48) month of the 3-month blanking period (p < .001). One year freedom from ATAs was 97.8% in patients without ERAT compared with 95.4%, 64.3%, and 8.3% in patients with ERAT in the first, second, and third months after the index procedure, respectively (p < .001). Hazard ratios of LR according to the timing of the last episode of ERAT first, second, and third months after the procedure were 2.84, 16.70, and 119.75, respectively.

CONCLUSIONS

The ERAT occurred in 49.0% of patients within the first 3 months after surgical ablation. The occurrence of ERAT within 3 months after surgical AF ablation was a significant independent predictor of LR. Hence, the currently accepted 3-month blanking period may be considered for redefining in patients with AF surgical ablation.

摘要

背景

在心房颤动(AF)导管消融后的 3 个月空白期内,常见房性心动过速(ATAs)。然而,关于 AF 手术后空白期目前的指南,证据很少。我们研究了早期复发性房性心动过速(ERAT)的发生率和意义,并评估了 AF 手术后最佳的空白期。

方法

收集了 2009 年至 2016 年间接受 AF 手术消融的 259 例患者的数据。ERAT 定义为持续 30s 的记录房性心动过速发作。采用多变量 Cox 比例风险模型评估 ERAT 作为 AF 晚期复发(LR)预测因子的作用。

结果

共有 127 例患者(49.0%)在 3 个月空白期的第 1(n=65)、第 2(n=14)或第 3 个月(n=48)经历了其最后一次 ERAT 发作(p<0.001)。无 ERAT 的患者 1 年无房性心动过速的比例为 97.8%,而有 ERAT 的患者在指数手术后第 1、第 2 和第 3 个月分别为 95.4%、64.3%和 8.3%(p<0.001)。根据 ERAT 最后一次发作的时间,LR 的风险比分别为第 1、第 2 和第 3 个月后 2.84、16.70 和 119.75。

结论

ERAT 在手术消融后 3 个月内发生在 49.0%的患者中。ERAT 在 AF 手术后 3 个月内的发生是 LR 的显著独立预测因子。因此,AF 手术消融患者目前接受的 3 个月空白期可能需要重新定义。

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