Horsfield K, Nicholls A, Cumming G, Hume M, Prowse K
Thorax. 1977 Jun;32(3):250-3. doi: 10.1136/thx.32.3.250.
Thirteen patients with a clinical diagnosis of pulmonary aspergillosis were treated with the anti-amoebic drug di-iodohydroxyquinoline, 1500-1800 mg/day orally, for 20 days. All were precipitin positive before treatment and all but one became negative after treatment. Sputum became negative in all of the 10 patients in whom it had been positive before treatment. Clinical improvement was marked in four patients, moderate in three, and slight in three, no change occurring in the remaining three. These results suggest that di-iodohydroxyquinoline may be of value in the treatment of pulmonary aspergillosis.
13例临床诊断为肺曲霉病的患者接受了抗阿米巴药物二碘羟基喹啉治疗，口服剂量为1500 - 1800毫克/天，持续20天。所有患者治疗前沉淀素均为阳性，治疗后除1例患者外其余均转为阴性。治疗前痰液阳性的10例患者痰液均转为阴性。4例患者临床改善明显，3例中度改善，3例轻度改善，其余3例无变化。这些结果表明二碘羟基喹啉可能对肺曲霉病的治疗有价值。
