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眼内抗生素治疗视网膜下脓肿的作用-病例报告及文献复习。

Role of Intralesional Antibiotic for Treatment of Subretinal Abscess - Case Report and Literature Review.

机构信息

Dr. Rajendra Prasad Centre for Ophthalmic Sciences, AIIMS, New Delhi, India.

出版信息

Ocul Immunol Inflamm. 2022 Feb 17;30(2):487-490. doi: 10.1080/09273948.2020.1811880. Epub 2020 Sep 18.

DOI:10.1080/09273948.2020.1811880
PMID:32946306
Abstract

PURPOSE

To describe a rare case of endogenous endophthalmitis due to Citrobacter with subretinal abscess and the role of the novel technique of intralesional antibiotic for its treatment.

METHODS

A retrospective case report.

RESULT

A 45-year-old male presenting with painful, progressive diminution of vision in the left eye was diagnosed to have endogenous endophthalmitis due to Citrobacter with subretinal abscess. After the failure of the initial intravitreal injection of ceftazidime and vancomycin, successful resolution of abscess was achieved by pars plana vitrectomy with 41-gauge (G) needle assisted intralesional injection of piperacillin and tazobactam combination.

CONCLUSION

We treated a case of Citrobacter associated endogenous endophthalmitis with subretinal abscess with intralesional injection of piperacillin and tazobactam combination. 41-G needle can be used safely to inject antibiotic into the subretinal space through a small self-sealing retinotomy with minimum risk of retinal detachment and encouraging results.

摘要

目的

描述一例罕见的由阴沟肠杆菌引起的眼内炎伴视网膜下脓肿,并探讨新型病灶内抗生素注射治疗的作用。

方法

回顾性病例报告。

结果

一名 45 岁男性因左眼疼痛、进行性视力下降就诊,被诊断为阴沟肠杆菌引起的眼内炎伴视网膜下脓肿。最初玻璃体腔内注射头孢他啶和万古霉素治疗失败后,采用 41G 针头辅助经睫状体平坦部玻璃体切除术,行病灶内注射哌拉西林他唑巴坦,成功解决了脓肿问题。

结论

我们采用哌拉西林他唑巴坦病灶内注射的方法成功治疗了一例阴沟肠杆菌相关性眼内炎伴视网膜下脓肿。41G 针头可通过小的自封闭视网膜切开术安全地将抗生素注入视网膜下间隙,发生视网膜脱离的风险最小,结果令人鼓舞。

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