Immunology, Hospital Ramón y Cajal Instituto Ramón y Cajal de Investigación Sanitaria (IRYCIS), Madrid, Spain.
Pathology, Hospital Ramón y Cajal IRYCIS, Madrid, Spain.
Clin Infect Dis. 2021 Dec 6;73(11):e3970-e3973. doi: 10.1093/cid/ciaa1422.
A woman with mild coronavirus disease 2019 developed cervical adenopathy, being diagnosed of Epstein-Barr virus infectious mononucleosis. We performed fine needle aspiration, and demonstrate that severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is found in lymph nodes even in mild disease along with a strong expansion of terminally differentiated effector memory CD4+ T cells, a cell population that is practically absent in lymph nodes.
一位患有轻度 2019 年冠状病毒病的女性出现颈部淋巴结病，被诊断为 EBV 感染性单核细胞增多症。我们进行了细针抽吸，结果表明，即使在轻度疾病中，也可以在淋巴结中发现严重急性呼吸综合征冠状病毒 2（SARS-CoV-2），并且终末分化效应记忆 CD4+T 细胞大量扩增，而这种细胞在淋巴结中实际上不存在。
