Institute of Nursing, Combined Military Hospital (CMH) Lahore Medical College, Pakistan.
Shifa Tameer-e-Millat University, Shifa College of Nursing, Islamabad, Pakistan.
Eur J Oncol Nurs. 2020 Oct;48:101826. doi: 10.1016/j.ejon.2020.101826. Epub 2020 Aug 19.
This study was undertaken to determine the effects of individualized education with support intervention on breast cancer patients' anxiety and depression while undergoing radiation therapy (RT). Moreover, the intervention was assessed for its feasibility in the context of Pakistan.
A quasi-experimental design was used to conduct this study in RT department of a public hospital in Karachi. A total of 61 breast cancer patients receiving radiation as adjuvant therapy participated in the study. The experimental group (n = 31) received individualized education with support in the form of face-to-face sessions and information booklet prior to the commencement of RT. In addition, the nurse remained available for the consultation during the RT sessions and on telephone throughout the RT period. However, the control group received only information booklet. Patients' anxiety and depression were measured in both of the groups before the commencement of RT, and at the completion of RT by using the Aga Khan University Anxiety and Depression Scale (AKUADS).
A significant reduction was found in the overall mean anxiety and depression scores of the experimental group (p = 0.000) from pre-test to post-test. The overall mean anxiety and depression scores of the control group showed no significant difference (p = 0.187). The effect size of the intervention was large (Cohen's d = 2.5).
The intervention was effective in reducing anxiety and depression among breast cancer patients receiving RT. Replication of the study on a larger scale in multiple settings on other cancer patients is recommended.
本研究旨在确定个体化教育支持干预对接受放射治疗（RT）的乳腺癌患者焦虑和抑郁的影响。此外，还评估了该干预措施在巴基斯坦的可行性。
采用准实验设计，在卡拉奇一家公立医院的 RT 科进行了这项研究。共有 61 名接受辅助放射治疗的乳腺癌患者参与了这项研究。实验组（n=31）在接受 RT 治疗前接受了个体化教育支持，形式为面对面课程和信息手册。此外，护士在 RT 治疗期间和整个 RT 期间都可通过电话提供咨询。然而，对照组只收到了信息手册。在 RT 治疗开始前和结束时，使用 Aga Khan 大学焦虑和抑郁量表（AKUADS）测量了两组患者的焦虑和抑郁情况。
实验组的总体平均焦虑和抑郁评分从预测试到后测试均显著降低（p=0.000）。对照组的总体平均焦虑和抑郁评分没有显著差异（p=0.187）。干预的效果显著（Cohen's d=2.5）。
该干预措施可有效减轻接受 RT 的乳腺癌患者的焦虑和抑郁。建议在其他癌症患者中在更大规模和多个环境中复制这项研究。
