[Electron microscopic study of the interaction of shigellae with cell cultures. III. Functional-structural changes in transplanted amniotic cells exposed to extracellular Flexner shigellae].

A quantitative changes of RNA and proteins and structural peculiarities of compensative-regenerative character were discovered in amnion cells subjected to the action of extracellular virulent shigellas by means of successive cytophotometry and electron microscopy. The long contact with the bacteria lead to increased degenerative changes in the cell cytoplasm. The arising changes seem to involve toxicity caused by the action of exometabolites of Shigella flexneri.