Section of Digestive Diseases, Department of Internal Medicine, Yale University School of Medicine, New Haven, CT, USA.
Department of Pathology, Kurume University School of Medicine, Kurume, Japan.
Clin Mol Hepatol. 2020 Oct;26(4):633-638. doi: 10.3350/cmh.2020.0179. Epub 2020 Sep 21.
The lymphatic system plays vital roles in interstitial fluid balance and immune cell surveillance. The effect of alcohol on the lymphatic system is poorly understood. This review article explores the role of the lymphatic system in the pathogenesis of alcohol-related disease including alcoholic liver disease (ALD) and the therapeutic potential of targeting hepatic lymphatics for the treatment of ALD.
淋巴系统在间质液平衡和免疫细胞监测中起着至关重要的作用。酒精对淋巴系统的影响还知之甚少。本文探讨了淋巴系统在酒精相关疾病（包括酒精性肝病，ALD）发病机制中的作用，以及针对肝内淋巴管治疗 ALD 的治疗潜力。
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