高效的[(NHC)Au(NTf)]催化的端炔和内炔的氢肼化反应。
Efficient [(NHC)Au(NTf)]-catalyzed hydrohydrazidation of terminal and internal alkynes.
作者信息
Heidrich Maximillian, Plenio Herbert
机构信息
Organometallic Chemistry, Technische Universität Darmstadt, Alarich-Weiss-Str. 12, 64287 Darmstadt, Germany.
出版信息
Beilstein J Org Chem. 2020 Aug 26;16:2080-2086. doi: 10.3762/bjoc.16.175. eCollection 2020.
Abstract
The efficient hydrohydrazidation of terminal (-, 18 examples, 0.1-0.2 mol % [(NHC)Au(NTf)], = 60 °C) and internal alkynes (-, 10 examples, 0.2-0.5 mol % [(NHC)Au(NTf)], = 60-80 °C) utilizing a complex with a sterically demanding bispentiptycenyl-substituted NHC ligand and the benign reaction solvent anisole, is reported.
摘要
报道了使用一种带有空间位阻较大的双戊并四烯基取代的NHC配体的配合物和良性反应溶剂苯甲醚，对末端炔烃（18个例子，0.1 - 0.2 mol% [(NHC)Au(NTf)]，温度 = 60 °C）和内炔烃（10个例子，0.2 - 0.5 mol% [(NHC)Au(NTf)]，温度 = 60 - 80 °C）进行高效氢化肼化反应。
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