Kim Hyun-Woo, Lim Kyeong-Ok, Lee Won-Pyo, Seo Yo-Seob, Shin Hong-In, Choi Seong-Ho, Kim Byung-Ock, Yu Sang-Joun
Department of Periodontology, School of Dentistry, Chosun University, Gwangju, Republic of Korea.
Department of Oral and Maxillofacial Radiology, School of Dentistry, Chosun University, Gwangju, Republic of Korea.
J Dent Sci. 2020 Sep;15(3):257-264. doi: 10.1016/j.jds.2020.06.004. Epub 2020 Jun 8.
BACKGROUND/PURPOSE: Due to the pneumatization of the maxillary sinus, the sinus floor augmentation is often performed to implant placement in the maxillary posterior region. The aim was to perform radiographic and histomorphometric evaluation after placement of mixed allografts (cortical freeze-dried bone allograft [FDBA] 50%:cancellous FDBA 50%) during sinus floor augmentation.
In 37 patients, anorganic bovine bone (ABB, sites = 16), mineralized cancellous bone allograft (MCBA, sites = 15), and mixed allografts (Mixed AG, sites = 20) were placed during sinus floor elevation via the lateral approach (LSFE), at total 51 sites with residual alveolar bone height (RBH) < 5 mm. Cone-beam computed tomography images were obtained before LSFE (T0), after surgery (T1), and 6 months after surgery (T2) for radiographic analysis. After a 6-month healing period, core biopsies were harvested and histomorphometric analysis was performed.
The mean augmented bone height (ABH) of ABB, MCBA, and mixed AG groups after surgery was similar (13.86 ± 4.19 mm, 13.99 ± 4.07 mm, and 14.20 ± 3.12 mm, respectively; > 0.05). The mean ABH of ABB, MCBA, and mixed AG groups after 6 months was similar (13.72 ± 4.55 mm, 11.83 ± 3.31 mm, and 12.53 ± 2.97 mm, respectively; > 0.05). In the ABB, MCBA, and mixed AG groups, the proportion of newly formed bone (NB) was similar (36.13 ± 10.01%, 39.26 ± 10.72%, and 31.27 ± 18.31%, respectively; > 0.05).
This result demonstrated that mixed AG led to sufficient bone augmentation and histologically comparable NB formation as compared to ABB and MCBA for sinus floor augmentation.
背景/目的：由于上颌窦气化，在上颌后牙区种植时常常需要进行窦底增高术。本研究旨在对上颌窦底增高术中植入混合同种异体骨移植物（皮质冻干骨同种异体移植物[FDBA]50%：松质骨FDBA 50%）后的影像学和组织形态计量学进行评估。
对37例患者，通过外侧入路行上颌窦底提升术（LSFE）时，分别植入无机牛骨（ABB，16个位点）、矿化松质骨同种异体移植物（MCBA，15个位点）和混合同种异体骨移植物（混合AG，20个位点），共51个位点，残余牙槽骨高度（RBH）<5mm。在LSFE术前（T0）、术后（T1）和术后6个月（T2）获取锥形束计算机断层扫描图像进行影像学分析。经过6个月的愈合期后，采集核心活检标本并进行组织形态计量学分析。
术后ABB、MCBA和混合AG组的平均增高骨高度（ABH）相似（分别为13.86±4.19mm、13.99±4.07mm和14.20±3.12mm；P>0.05）。6个月后ABB、MCBA和混合AG组的平均ABH相似（分别为13.72±4.55mm、11.83±3.31mm和12.53±2.97mm；P>0.05）。在ABB、MCBA和混合AG组中，新形成骨（NB）的比例相似（分别为36.13±10.01%、39.26±10.72%和31.27±18.31%；P>0.05）。
该结果表明，与ABB和MCBA相比，混合AG在上颌窦底增高术中能导致足够的骨增量，且在组织学上新形成骨的形成相当。
