Macho Viviana Marisa Pereira, de Barros Menéres Manso Maria Conceição Antas, E Silva Diana Maria Veloso, de Andrade David José Casimiro
Pediatric Dentistry, Faculty of Dentistry, University of Porto, Porto, Portugal.
Department of Biotechnology, Faculty of Health Sciences, UFP Energy, Environment and Health Research Unit (FP-ENAS), University Fernando Pessoa, Porto, Portugal.
J Dent Sci. 2020 Sep;15(3):345-350. doi: 10.1016/j.jds.2020.02.006. Epub 2020 Mar 28.
BACKGROUND/PURPOSE: Dental enamel defects are related to celiac disease and the dentists are in a perfect situation to identify and report suspected cases. The aim was to evaluate the symmetry of enamel defects in a pediatric Portuguese population with celiac disease and compare it with healthy controls.
a case-control study was performed in 80 patients with celiac disease and 80 healthy individuals aged 6-18 years old as controls. Data was collected by a questionnaire and clinical observation. Colour, type, and site of enamel defects were recorded and classified according to Aine criteria. Data analysis was performed, and any p-value <0.05 was considered significant.
Enamel defects were found in 55% of patients with celiac disease and 27.5% in the control individuals (p < 0.001). Grade I of Aine's classification was the most found in both groups, but it was higher in the celiac disease group, not only in the permanent dentition, but also in both dentitions with statistically significant difference (p = 0.002 and p = 0.001 respectively). Grade II was found only in the celiac disease group. It was observed that enamel defects in celiac disease were symmetric and the most affected teeth were the first permanent molars (p = 0.003) and the permanent incisors (p = 0.001).
Symmetric dental enamel defects in population with celiac disease are more predominant than in general population. Therefore, individuals with enamel defects, especially those with symmetric lesions, should be well evaluated and the possibility of having celiac disease in the clinical history must be taken into account.
背景/目的：牙釉质缺陷与乳糜泻有关，牙医处于识别和报告疑似病例的理想位置。目的是评估患有乳糜泻的葡萄牙儿童人群中牙釉质缺陷的对称性，并将其与健康对照组进行比较。
对80例乳糜泻患者和80名6至18岁的健康个体作为对照组进行了病例对照研究。通过问卷调查和临床观察收集数据。根据艾内标准记录并分类牙釉质缺陷的颜色、类型和部位。进行数据分析，任何p值<0.05被认为具有统计学意义。
55%的乳糜泻患者发现有牙釉质缺陷，对照组为27.5%（p<0.001）。两组中艾内分类的I级最为常见，但乳糜泻组更高，不仅在恒牙列中，而且在两个牙列中均有统计学显著差异（分别为p = 0.002和p = 0.001）。II级仅在乳糜泻组中发现。观察到乳糜泻患者的牙釉质缺陷是对称的，受影响最严重的牙齿是第一恒磨牙（p = 0.003）和恒切牙（p = 0.001）。
患有乳糜泻人群中的对称性牙釉质缺陷比一般人群更普遍。因此，有牙釉质缺陷的个体，尤其是那些有对称性病变的个体，应进行充分评估，并且必须考虑临床病史中患乳糜泻的可能性。
