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在同一手术中对肾性骨病继发的脆性骨折进行双极半关节置换术和甲状旁腺切除术。

Bipolar Hemiarthroplasty and Parathyroidectomy at the Same Setting for Fragility Fractures Secondary to Renal Bone Disease.

作者信息

Silva Amila, Tay Adriel You Wei, Ng Chung Fai Jeremy, Howe Tet Sen

机构信息

Department of Orthopaedic Surgery, Singapore General Hospital, 20 College Road, Outram Road, Academia, Level 4, Singapore, 169856 Singapore.

Department of General Surgery, Singapore General Hospital, Outram Road, Singapore, 169608 Singapore.

出版信息

Indian J Orthop. 2020 Jun 3;54(Suppl 1):81-86. doi: 10.1007/s43465-020-00153-z. eCollection 2020 Sep.

Abstract

BACKGROUND

From 1980s to the new millennium, the number of patients surviving with end stage renal disease (ESRD) has increased by 3 fold. This is driven by early detection of primordial and primary risk factors, state of the art renal replacement therapy and ease of public access to healthcare. Renal osteodystrophy (RO) is a metabolic bone disease causing significant morbidity in patients with ESRD, in particular fragility fractures. In this case series, we present the surgical management of 3 ESRD patients with pathological fractures of the neck of femur (NOF) and surgical treatment (parathyroidectomy) of tertiary hyperparathyroidism of ESRD patients in the same surgical setting. Up to date there has been no reports on bipolar hemiarthroplasty and total parathyroidectomy implemented in the same operative setting.

METHODS

We present 3 cases, 2 males and a female with an average age of 48 years. All patients presented with no trauma or minimal trauma. With high index of suspicion and after confirming the diagnosis with advanced imaging, the patients underwent cemented modular hemiarthroplasty with posterior approach. Parathyroidectomy was sequentially performed to address the tertiary hyperparathyroidism at the same setting. We followed them for 48 months.

RESULTS

At 48-month follow up, all the patients were at their pre-morbid ambulatory status and there were no major complications. They did not need any revision surgery or re-operation either for the hemiarthroplasty surgery or the parathyroidectomy during the follow up period.

CONCLUSION

To avoid diagnostic pitfalls in this group of patients we recommend MRIs of both hips in patients complaining of unilateral hip pain even when the roentgenograms are clear of fractures. Total parathyroidectomy at the same setting with the bipolar hemi-arthroplasty is a safe combination. This reduces the anaesthesia risk, the recovery time as well as the equilibrium time for calcium homeostasis.

摘要

背景

从20世纪80年代到新千年,终末期肾病(ESRD)存活患者数量增加了两倍。这得益于对原始和主要危险因素的早期检测、先进的肾脏替代疗法以及公众获得医疗保健的便利性。肾性骨营养不良(RO)是一种代谢性骨病,在ESRD患者中导致显著的发病率,尤其是脆性骨折。在本病例系列中,我们展示了3例ESRD患者股骨颈(NOF)病理性骨折的手术治疗以及同一手术环境下ESRD患者继发性甲状旁腺功能亢进的手术治疗(甲状旁腺切除术)。迄今为止,尚无关于在同一手术环境中实施双极半关节置换术和全甲状旁腺切除术的报道。

方法

我们呈现3例病例,2例男性和1例女性,平均年龄48岁。所有患者均无创伤或仅有轻微创伤。由于高度怀疑并经先进影像学确诊后,患者采用后路骨水泥型模块化半关节置换术。在同一环境下依次进行甲状旁腺切除术以治疗继发性甲状旁腺功能亢进。我们对他们进行了48个月的随访。

结果

在48个月的随访中,所有患者均处于病前的活动状态,且无重大并发症。在随访期间,他们无需因半关节置换术或甲状旁腺切除术进行任何翻修手术或再次手术。

结论

为避免该组患者的诊断陷阱,我们建议即使X线片未显示骨折,对于主诉单侧髋部疼痛的患者,应进行双髋MRI检查。在同一环境下将全甲状旁腺切除术与双极半关节置换术联合是一种安全的组合。这降低了麻醉风险、恢复时间以及钙稳态的平衡时间。

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