Colorado Center for Bone Research, 3190 S. Wadsworth Boulevard, Lakewood, CO 80227, USA.
Cleve Clin J Med. 2009 Dec;76(12):715-23. doi: 10.3949/ccjm.76a.08108.
When a patient with chronic kidney disease suffers a fragility fracture, a key question is whether the patient has osteoporosis or, instead, renal osteodystrophy. Bone densitometry does not help in this distinction: biochemical tests, and sometimes also bone biopsy, are needed. However, even if the patient has osteoporosis, we have little evidence to guide our treatment decisions in cases of advanced chronic kidney disease.
当慢性肾脏病患者发生脆性骨折时，一个关键问题是患者是否患有骨质疏松症，还是患有肾性骨营养不良。骨密度测定在此类鉴别中并无帮助：需要进行生化检查，有时还需要进行骨活检。然而，即使患者患有骨质疏松症，在晚期慢性肾脏病患者中，我们也几乎没有证据来指导我们的治疗决策。
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