Ağababaoğlu İsmail, Ersöz Hasan, Yıldız Özgür Ömer, Şimşek Gökçen, Sanioğlu Selim Yavuz, Karaoğlanoğlu Nurettin
Department of Thoracic Surgery, Yıldırım Beyazıt University, Yenimahalle Training and Research Hospital, Ankara, Turkey.
Department of Thoracic Surgery, Katip Çelebi University, Medicine Faculty, Izmir, Turkey.
Turk Gogus Kalp Damar Cerrahisi Derg. 2020 Jul 28;28(3):480-487. doi: 10.5606/tgkdc.dergisi.2020.18884. eCollection 2020 Jul.
This study aims to compare the results of the open surgical approach versus endobronchial conical stent application in the treatment of extensive fistulas.
Between December 2004 and April 2016, a total of 36 patients (34 males, 2 females; mean age 59.6±8.1 years; range, 40 to 72 years) with a bronchopleural fistula of ≥8 mm in diameter and underwent either conventional open surgery with stump-supported intercostal muscle flap or endobronchial ultra-flex expandable stenting were retrospectively analyzed. The demographic and clinical characteristics of the patients, operative data including the length of hospital stay, thoracic drainage time, and early mortality, and survival data were recorded.
The mean hospitalization time was 17.4±4.5 days for the bronchoscopic group and 22.5±6.7 days for the invasive surgery group (p=0.026). The median time to removal of thoracic drains was 15 (range, 10 to 30) days for the bronchoscopic group and 26 (range, 14 to 55) days for the surgical group (p=0.027). Early mortality rates of both approaches were in favor of the bronchoscopic approach (χ=7.058; p=0.008). Two-year survival rate was 76.47% (n=13) in the bronchoscopic group and 70% (n=7) in the surgical group. There was no statistically significant difference in the survival rates between the two groups (χ=0.132; p=0.716).
Our study results suggest that bronchoscopic approach can be the first choice in the treatment algorithm of fistulas with a diameter of ≥8 mm presenting with empyema in selected cases.
本研究旨在比较开放手术方法与支气管内锥形支架置入术治疗广泛瘘管的效果。
回顾性分析2004年12月至2016年4月期间,共36例(男34例,女2例;平均年龄59.6±8.1岁;范围40至72岁)直径≥8mm的支气管胸膜瘘患者,这些患者接受了传统的开放手术(采用残端支撑肋间肌瓣)或支气管内超弹性可扩张支架置入术。记录患者的人口统计学和临床特征、手术数据(包括住院时间、胸腔引流时间和早期死亡率)以及生存数据。
支气管镜组的平均住院时间为17.4±4.5天,侵入性手术组为22.5±6.7天(p=0.026)。支气管镜组胸腔引流管拔除的中位时间为15天(范围10至30天),手术组为26天(范围14至55天)(p=0.027)。两种方法的早期死亡率均有利于支气管镜检查法(χ=7.058;p=0.008)。支气管镜组的两年生存率为76.47%(n=13),手术组为70%(n=7)。两组生存率之间无统计学显著差异(χ=0.132;p=0.716)。
我们的研究结果表明,在某些选定病例中,对于直径≥8mm且伴有脓胸的瘘管,支气管镜检查法可作为治疗方案的首选。