Alay Ismail, Yildiz Sukru, Kaya Cihan, Yasar Kadriye Kart, Aydin Ozlem Altuntas, Karaosmanoglu Hayat Kumbasar, Aydeniz Banu, Salihoglu Ozgul, Yaşar Levent, Ekin Murat
Department of Obstetrics and Gynecology, University of Health Sciences Turkey, Bakirkoy Dr. Sadi Konuk Education and Training Hospital, Istanbul, Turkey.
Department of Infectious Diseases and Clinical Microbiology, University of Health Sciences Turkey, Bakirkoy Dr.Sadi Konuk Education and Training Hospital, Istanbul, Turkey.
J Obstet Gynaecol Res. 2020 Dec;46(12):2552-2560. doi: 10.1111/jog.14493. Epub 2020 Sep 21.
To observe the clinical course of symptomatic pregnant women diagnosed with or suspected of having COVID-19.
This study analyzed the clinical and laboratory results of 27 patients with real-time polymerase chain reaction (RT-PCR)-confirmed COVID-19 and 25 patients with a suspected COVID-19 diagnosis based on their symptoms and chest computed tomography (CT) findings. The patients' coagulation parameters and acute-phase reactants were evaluated both before and after treatment. The maternal and neonatal outcomes were also reviewed.
The mean duration of hospitalization was 6.1 ± 3 days. The gestational age of the patients ranged from 6w2d to 40w2d. Thirty-five patients' CT scan findings suggested viral pneumonia. Four patients delivered vaginally, and 10 patients underwent a cesarean section during the study period. Four of the cesarean deliveries were indicated due to COVID-19 hypoxemia-related fetal distress. Four patients were admitted to the intensive care unit (ICU) after the cesarean section.
Early hospitalization and medical treatment can alleviate symptoms, improve the clinical course and reduce the need for ICU in symptomatic pregnant patients with suspected or confirmed COVID-19. Chest CT scans are a suitable option for suspected but unconfirmed COVID-19 infection.
观察确诊或疑似新型冠状病毒肺炎(COVID-19)的有症状孕妇的临床病程。
本研究分析了27例经实时聚合酶链反应(RT-PCR)确诊为COVID-19的患者以及25例根据症状和胸部计算机断层扫描(CT)结果疑似COVID-19诊断的患者的临床和实验室检查结果。在治疗前后评估患者的凝血参数和急性期反应物。还回顾了母婴结局。
平均住院时间为6.1±3天。患者的孕周范围为6周2天至40周2天。35例患者的CT扫描结果提示病毒性肺炎。在研究期间,4例患者经阴道分娩,10例患者接受了剖宫产。其中4例剖宫产是由于COVID-19低氧血症相关的胎儿窘迫。4例患者在剖宫产后被收入重症监护病房(ICU)。
对于疑似或确诊COVID-19的有症状孕妇,早期住院和治疗可缓解症状、改善临床病程并减少入住ICU的需求。胸部CT扫描是疑似但未确诊COVID-19感染的合适检查方法。