School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang, P.R. China.
School of Chinese Materia Medica and Tianjin State Key Laboratory of Modern Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin, P.R. China.
Nat Prod Res. 2022 Apr;36(7):1820-1826. doi: 10.1080/14786419.2020.1819268. Epub 2020 Sep 21.
The chemical investigation of the fruits of (Asteraceae) led to the isolation of two new -kauranoid glucosides named 2--(6--isocaleryl--D-glucopyranosyl) atractyligenin () and 2--(2--isovaleryl--D-glucopyranosyl) atractyligenin (), together with one known compound. Their structures were established by comprehensive spectroscopic analysis coupled with single-crystal X-ray diffraction and electronic circular dichroism data. All compounds and their aglycone were evaluated for their anti-proliferative activities against three human cancer cell lines.
对（菊科）果实的化学研究导致分离出两种新的 - 卡诺醇葡萄糖苷，分别命名为 2--(6--异十六酰基--D-吡喃葡萄糖基) 苍术苷元和 2--(2--异戊酰基--D-吡喃葡萄糖基) 苍术苷元（），以及一种已知化合物。通过综合光谱分析结合单晶 X 射线衍射和电子圆二色性数据确定了它们的结构。所有化合物及其糖苷配基均针对三种人癌细胞系的抗增殖活性进行了评估。
