Centre for Health Economics, University of York, York, UK.
Department of Economics and Related Studies, University of York, New York, UK.
Expert Rev Pharmacoecon Outcomes Res. 2021 Aug;21(4):729-736. doi: 10.1080/14737167.2020.1812387. Epub 2020 Sep 20.
Current health economic analysis guidelines emphasize the importance of using nationally appropriate cost and valuation inputs. However, some countries lack national data, and some analyses focus on interventions with costs and benefits at regional or global scales.
Recognizing the need for better estimates of appropriate values for application at these levels than those used in the past, we characterize population-weighted dollar per disability-adjusted life year (DALY) averted by World Bank Income Level based on available national estimates of the marginal productivity of the healthcare system.
The defaults suggested here reflect health opportunity costs across countries more consistent with existing evidence than those previously used or recommended. As countries change income levels and healthcare spending, and as additional or updated marginal productivity of healthcare expenditure estimates become available, we expect the defaults to change.
The best option for informing decisions around resource allocation in health care such that they improve health outcomes overall remains the use of time-appropriate country-specific estimates of the marginal productivity of the healthcare system. Instead of single, time-invariant defaults, health economists should seek to develop valuation inputs that better account for health opportunity costs and do so over time.
当前的健康经济分析指南强调了使用适合国家的成本和估值投入的重要性。然而,一些国家缺乏国家数据,而一些分析则侧重于在区域或全球范围内具有成本和效益的干预措施。
认识到需要更好地估计适用于这些层面的适当价值,而不是过去使用的价值,我们根据可获得的医疗保健系统边际生产力的国家估计,以世界银行收入水平为基础,对每避免一个残疾调整生命年(DALY)的美元进行了加权人口特征描述。
这里建议的默认值反映了各国之间的健康机会成本,比过去使用或建议的默认值更符合现有证据。随着国家收入水平和医疗保健支出的变化,以及更多或更新的医疗保健支出边际生产力估计的出现,我们预计默认值将发生变化。
为了改善整体健康结果,为医疗保健资源分配提供决策信息的最佳选择仍然是使用适合国家的、具有时间性的医疗保健系统边际生产力的具体估算。健康经济学家不应寻求单一的、不变的默认值,而应寻求开发更好地考虑健康机会成本的估值投入,并随着时间的推移不断改进。