University of Tartu, Institute of Education, Näituse 2, Tartu, Estonia.
University of Tartu, Institute of Psychology, Ravila 14A Chemicum, Tartu, Estonia.
Neurosci Lett. 2020 Nov 1;738:135397. doi: 10.1016/j.neulet.2020.135397. Epub 2020 Sep 19.
Attention distractibility in a low load visual search experiment with a rare irrelevant distractor could be an objective continuous measure in adulthood that correlates well with the symptoms of attention deficit throughout lifespan. This was studied using a birth cohort representative sample in a longitudinal study. The expected correlations were not found between the distractor cost measured in the experiment in adulthood and the inattention questionnaire scores from ages 15-33. However, the coefficient of variability for RT (CVRT) correlated negatively with self-reported motor restlessness (age 15) and attention deficit (age 25). We suggest that hyperactivity in childhood improved motor control at age 33. Associations with the gene KTN1 rs945270 (found to affect putamen size) were explored. CVRT, motor restlessness at age 15 and attention deficit scores at age 25 were especially low for male C-allele carriers. A possible association with the volume of putamen of individual participants is considered.
在一项低负荷视觉搜索实验中，对罕见无关分心物的注意力分散，可能是一种与整个生命周期注意力缺陷症状密切相关的成人客观连续测量指标。这是使用一个具有代表性的出生队列纵向研究进行的研究。在成年期进行的实验中测量的分心成本与 15-33 岁时的不注意问卷得分之间，并未发现预期的相关性。然而，反应时的变异性系数（CVRT）与自我报告的运动不安（15 岁）和注意力缺陷（25 岁）呈负相关。我们认为，儿童时期的多动在 33 岁时改善了运动控制。探索了与基因 KTN1 rs945270 的关联（发现其影响壳核大小）。对于男性 C 等位基因携带者，CVRT、15 岁时的运动不安和 25 岁时的注意力缺陷评分尤其低。考虑了与个体参与者壳核体积的可能关联。
