电针治疗中风后吞咽困难：一项随机对照试验的系统评价与Meta分析方案
Electroacupuncture for post-stroke dysphagia: A protocol for systematic review and meta-analysis of randomized controlled trials.
作者信息
Han Chang-Ho, Kim Jeong Hwa, Kim Mikyung, Kim Ha-Ri, Kim Seo Young, Choi Hyun-Young, Jin Chul, Kwon Seungwon, Jung Woo-Sang, Moon Sang-Kwan, Park Jung-Mi, Ko Chang-Nam, Cho Seung-Yeon
机构信息
Department of Internal Medicine, College of Korean Medicine, Dongguk University, Gyeongju.
Department of Clinical Korean Medicine, Graduate School, Kyung Hee University, Seoul.
出版信息
Medicine (Baltimore). 2020 Sep 18;99(38):e22360. doi: 10.1097/MD.0000000000022360.
BACKGROUND
Post-stroke dysphagia (PSD) requires effective treatment as it may cause aspiration pneumonia, dehydration, or malnutritution, which can increase the length of hospital stay as well as mortality. In the field of stroke, electroacupuncture (EA) has been widely used, and a number of clinical research papers have been published regarding its effects. This systematic review aims to evaluate the effectiveness of EA for the treatment of PSD.
METHODS
Randomized controlled trials evaluating the use of EA in PSD will be included in this meta-analysis. The following electronic databases will be searched from inception to July 31, 2020, using terms relating to EA and PSD: PubMed, the Cochrane Library, the Excerpta Medica Database, China National Knowledge Infrastructure, the Korean Medical Database, KoreaMed, the National Digital Science Library, and the Oriental Medicine Advanced Searching Integrated System. Two reviewers will independently search these databases, select studies for inclusion, and evaluate the quality of the studies. Methodological quality will be assessed using the Cochrane Handbook for Systematic Reviews of Interventions (version 6.0). The primary outcome will be the total effective rate; secondary outcomes will include results of other assessments of dysphagia such as the water drinking test scale and videofluoroscopic swallowing study. We will also investigate the number and severity of adverse events. The Cochrane Review Manager (RevMan) software (version 5.3.5) will be employed to assess bias risk, data integration risk, and meta-analysis risk. Mean difference and standardized mean difference will be used to represent continuous data, while risk ratios will be used for pooled binary data.
RESULTS
This study will provide a comprehensive review and evaluation of the available evidence regarding the efficacy and safety of EA as a treatment for PSD.
CONCLUSION
This study will clarify whether EA could be an effective and safe treatment for PSD.
背景
中风后吞咽困难（PSD）需要有效治疗，因为它可能导致吸入性肺炎、脱水或营养不良，进而增加住院时间和死亡率。在中风领域，电针（EA）已被广泛应用，并且已经发表了许多关于其疗效的临床研究论文。本系统评价旨在评估电针治疗PSD的有效性。
方法
本荟萃分析将纳入评估电针在PSD中应用的随机对照试验。将使用与电针和PSD相关的术语，从数据库建立至2020年7月31日，检索以下电子数据库：PubMed、Cochrane图书馆、医学文摘数据库、中国知网、韩国医学数据库、KoreaMed、国家数字科学图书馆和东方医学高级检索集成系统。两名评价者将独立检索这些数据库，选择纳入研究，并评估研究质量。将使用《Cochrane干预措施系统评价手册》（第6.0版）评估方法学质量。主要结局将是总有效率；次要结局将包括吞咽困难的其他评估结果，如水吞咽试验量表和电视荧光吞咽造影检查。我们还将调查不良事件的数量和严重程度。将使用Cochrane系统评价管理器（RevMan）软件（5.3.5版）评估偏倚风险、数据整合风险和荟萃分析风险。均值差和标准化均值差将用于表示连续数据，而风险比将用于汇总二分类数据。
结果
本研究将对电针作为PSD治疗方法的有效性和安全性的现有证据进行全面综述和评价。
结论
本研究将阐明电针是否可能是一种有效且安全的PSD治疗方法。
Zotero 插件