Meuleman E A, Bayne C J, van der Knaap W P
Prog Clin Biol Res. 1987;233:113-27.
After penetration into its snail host the trematode not only has to find a suitable environment, it also has to circumvent the activities of its host's internal defence system to survive and to develop normally. Immunological compatibility of snails and trematodes is dependent on the capability of the parasite to evade and/or suppress the defence activities of its host. The possible role of physicochemical properties of the surfaces of the parasite and the host defence cells in evasion of host responses remains unknown; a role is indicated for molecular mimicry in the miracidium and the young mother sporocyst and for masking in the cercaria. Strong evidence exists that trematodes secrete substances which suppress anti-trematode activities of snail haemocytes.
吸虫侵入蜗牛宿主后，不仅要找到合适的生存环境，还必须规避宿主内部防御系统的活动，才能存活并正常发育。蜗牛与吸虫之间的免疫相容性取决于寄生虫逃避和/或抑制宿主防御活动的能力。寄生虫和宿主防御细胞表面的物理化学性质在逃避宿主反应中的可能作用尚不清楚；有迹象表明，毛蚴和幼母胞蚴中存在分子模拟现象，而尾蚴中存在掩盖现象。有确凿证据表明，吸虫会分泌抑制蜗牛血细胞抗吸虫活性的物质。
