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[影响蜗牛-吸虫系统中宿主-寄生虫关系的免疫机制]

[Immunologic mechanisms influencing the host-parasite relations in snail-trematode systems].

作者信息

Kofta W

出版信息

Wiad Parazytol. 1994;40(3):229-51.

PMID:7801639
Abstract

This is a review article based on about 100 papers from leading world newspapers. The main features and the way of action of the snail's immune system are described. The mechanisms of discrimination between self and non-self are presented in detail, including characterization of interacting components of host (cellular and humoral factors) and parasite (a sporocyst surface) origin. The phenomena of molecular disguise and molecular mimicry are discussed in the context of the compatibility between a host and a parasite. The possible ways of killing parasite are indicated, with special regard to production of reactive oxygen intermediates by hemocytes during the process of killing.

摘要

这是一篇基于约100篇来自世界主要报纸的论文撰写的综述文章。文中描述了蜗牛免疫系统的主要特征及其作用方式。详细介绍了自我与非自我的识别机制,包括宿主(细胞和体液因子)和寄生虫(孢子囊表面)来源的相互作用成分的特征。在宿主与寄生虫相容性的背景下讨论了分子伪装和分子模拟现象。指出了杀死寄生虫的可能方式,特别关注血细胞在杀伤过程中产生活性氧中间体的情况。

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