[Regulation of the endocrine system].

The universal significance of the endocrine system for the regulation of the vital functions and the extra ordinarily high biological activity of the hormones require sensitive mechanisms of regulation within this system. The central nervous system is integrated into these regulatory processes and controls by neurotransmitters and hypothalamic releasing and inhibiting of the hormones the secretion of the hypophyseal and peripheral hormones. Central and peripheral feed-back mechanisms making possible the adaptation of the neuroendocrine system to changing external and internal conditions are operative between the peripheral endocrine glands and the hypothalamo-hypophyseal system as well as during synthesis, transport, action and metabolism of hormones. The knowledge of the fundamental regulatory mechanisms is a presupposition for the effective diagnosis and therapy of endocrine dysfunctions.