Division of Pediatric Hematology/Oncology/BMT, Nationwide Children's Hospital, Columbus, Ohio, USA.
Department of Pediatrics, The Ohio State University, Columbus, Ohio, USA.
J Adolesc Young Adult Oncol. 2021 Jun;10(3):282-287. doi: 10.1089/jayao.2020.0113. Epub 2020 Sep 22.
Medication adherence research involving adolescent and young adult (AYA) oncology patients has consisted of small, retrospective studies demonstrating poor adherence rates. Technology plays an active role in attempt to improve medication adherence. There is a growing body of literature investigating the role of smartphone applications (apps). We hypothesized a medication phone app, MedActionPlan Pro (MPP), leads to perceived improvement in medication adherence. Thirty AYA oncology patients actively receiving treatment (AYA defined as 15-30 years) at Nationwide Children's Hospital were enrolled. Participants downloaded the MPP app on their smartphone for 3 months, during which time participants were provided text messages and alerts to encourage medication adherence. Post-app use, participants completed semi-structured interviews. Interviews were audio-recorded, transcribed, and independently coded to determine consensus thematic content. Thirty AYA oncology participants (16 male), median age 17.5 (range: 15-30 years), participated in the study, with 22 participants (55% male) with a median age of 18 years (range: 15-30 years) participated in the final qualitative survey interview. Participants reported positive views about app utilization and perceived improved medication adherence. Additional themes included perceived decreased forgetfulness, improved organization, and identified customization for medications within the app was most important to AYAs. AYA oncology patients reported improvement in perceived medication adherence utilizing MPP and identified several features they thought would lead to improved medication adherence. These findings, integrated with previous literature, support the further need to investigate the utility of medication adherence apps that fit the unique needs of AYA oncology patients.
涉及青少年和年轻成人（AYA）肿瘤患者的药物依从性研究包括小型回顾性研究，这些研究表明药物依从率较低。技术在试图改善药物依从性方面发挥着积极的作用。越来越多的文献研究了智能手机应用程序（apps）的作用。我们假设使用药物手机应用程序 MedActionPlan Pro（MPP）可提高药物依从性。
全美儿童医院（Nationwide Children's Hospital）有 30 名正在积极接受治疗的 AYA 肿瘤患者（定义为 15-30 岁）入组。参与者在他们的智能手机上下载了 MPP 应用程序，为期 3 个月，在此期间，参与者会收到短信和提醒以鼓励他们按时服药。使用应用程序后，参与者完成了半结构化访谈。访谈进行了录音、转录，并进行了独立编码，以确定共识主题内容。
30 名 AYA 肿瘤参与者（16 名男性），中位年龄 17.5 岁（范围：15-30 岁），参与了研究，其中 22 名参与者（55%为男性）中位年龄为 18 岁（范围：15-30 岁）参加了最终的定性调查访谈。参与者对应用程序的使用表示积极，并认为药物依从性有所提高。其他主题包括感知到的健忘减少、改善的组织性，以及参与者认为应用程序内针对药物的定制功能对 AYA 最重要。
AYA 肿瘤患者报告说，使用 MPP 可提高他们对药物依从性的感知，并确定了他们认为可以提高药物依从性的几个特征。这些发现与之前的文献相结合，支持进一步研究适合 AYA 肿瘤患者独特需求的药物依从性应用程序的实用性。
