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食管癌术后出院标准:国际专家德尔菲共识。

Fit-for-Discharge Criteria after Esophagectomy: An International Expert Delphi Consensus.

机构信息

Department of Visceral and Transplant Surgery, University Hospital Zurich, Zurich, Switzerland.

IRCCS Policlinico San Donato, Division of General and Foregut Surgery, Department of Biomedical Sciences for Health, University of Milan, Milan, Italy.

出版信息

Dis Esophagus. 2021 Jun 14;34(6). doi: 10.1093/dote/doaa101.

Abstract

There are no internationally recognized criteria available to determine preparedness for hospital discharge after esophagectomy. This study aims to achieve international consensus using Delphi methodology. The expert panel consisted of 40 esophageal surgeons spanning 16 countries and 4 continents. During a 3-round, web-based Delphi process, experts voted for discharge criteria using 5-point Likert scales. Data were analyzed using descriptive statistics. Consensus was reached if agreement was ≥75% in round 3. Consensus was achieved for the following basic criteria: nutritional requirements are met by oral intake of at least liquids with optional supplementary nutrition via jejunal feeding tube. The patient should have passed flatus and does not require oxygen during mobilization or at rest. Central venous catheters should be removed. Adequate analgesia at rest and during mobilization is achieved using both oral opioid and non-opioid analgesics. All vital signs should be normal unless abnormal preoperatively. Inflammatory parameters should be trending down and close to normal (leucocyte count ≤12G/l and C-reactive protein ≤80 mg/dl). This multinational Delphi survey represents the first expert-led process for consensus criteria to determine 'fit-for-discharge' status after esophagectomy. Results of this Delphi survey may be applied to clinical outcomes research as an objective measure of short-term recovery. Furthermore, standardized endpoints identified through this process may be used in clinical practice to guide decisions regarding patient discharge and may help to reduce the risk of premature discharge or prolonged admission.

摘要

目前尚无国际公认的标准来确定食管癌手术后出院的准备情况。本研究旨在使用德尔菲法达成国际共识。专家小组由来自 16 个国家和 4 个大洲的 40 名食管外科医生组成。在三轮基于网络的德尔菲调查中,专家使用 5 分制李克特量表对出院标准进行投票。使用描述性统计数据对数据进行分析。如果在第 3 轮中达成≥75%的共识,则达成共识。以下基本标准达成共识:患者通过口服至少液体加可选经空肠喂养管补充营养来满足营养需求。患者应该已经放屁,在活动或休息时不需要吸氧。应去除中心静脉导管。通过口服阿片类药物和非阿片类镇痛药实现休息和活动时的充分镇痛。除非术前异常,否则所有生命体征均应正常。炎症参数应呈下降趋势并接近正常(白细胞计数≤12G/l 和 C 反应蛋白≤80mg/dl)。这项多国家德尔菲调查代表了首次由专家主导的共识标准制定过程,用于确定食管癌手术后的“出院适宜性”。这项德尔菲调查的结果可以作为短期恢复的客观指标应用于临床结果研究。此外,通过这一过程确定的标准化终点可以在临床实践中用于指导患者出院决策,并有助于降低过早出院或住院时间延长的风险。

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