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尼日利亚社区药店机会性心血管疾病危险因素筛查:一项横断面研究。

Opportunistic screening of cardiovascular disease risk factors in community pharmacies in Nigeria: a cross-sectional study.

机构信息

Department of Medicine, College of Medicine, University of Lagos, Idi-Araba, Lagos, Nigeria.

Victory Drugs Ltd, Festac, Lagos, Nigeria.

出版信息

Int J Clin Pharm. 2020 Dec;42(6):1469-1479. doi: 10.1007/s11096-020-01112-2. Epub 2020 Sep 22.

Abstract

Background Early identification and treatment of cardiovascular disease (CVD) risk factors through screening are crucial in the primary prevention of CVD and reduction in healthcare-related costs. Use of Non-Physician Healthcare-workers including Community Pharmacists has been advocated as an effective and cost-efficient model of healthcare delivery. In Nigeria the use of community pharmacists for mass screening of CVD risk factors has not been explored. Objective We sought to investigate the possibility of mass CVD risk factor screening in community pharmacies by pharmacists. Setting Lagos, Nigeria. Methods Between October and December 2018 eight hundred and eighty-nine apparently healthy participants were screened for obesity, hypertension, diabetes and hypercholesterolaemia in ten community pharmacies. Diabetes and hypercholesterolaemia were screened for using point-of-care testing modalities. A structured questionnaire was used to obtain the socio-demographic data of the participants. Main outcome measures Prevalence of overweight/obesity, hypertension, diabetes, hypercholesterolaemia, smoking and alcohol intake. Results Mean age of the subjects was 56.8 ± 21.1 years. Majority (57.4%) were females. Prevalence of smoking and alcohol intake were 4.3% and 26.7% respectively. 59.7% and 71.5% of males and females were either overweight (BMI ≥ 25 kg/m) or obese (BMI ≥ 30 kg/m) respectively. Prevalence of hypertension was 28.2% in all subjects, 30.9% in males and 26.3% in females, p < 0.001. Using BP > 130/80 mmHg prevalence of hypertension was 55.1%. Diabetes was detected in 3% of the subjects while 45.3% had hypercholesterolaemia. In total, 64.1% of the subjects were diagnosed with CVD risk factors for the first time. Conclusion Opportunistic screening for CVD risk factors is possible in community pharmacies and has the ability to detect previously undiagnosed risk factors. This community pharmacy based model could serve as a cost-effective approach to primary prevention of CVD.

摘要

背景

通过筛查及早识别和治疗心血管疾病(CVD)风险因素对于 CVD 的一级预防和降低医疗保健相关成本至关重要。提倡使用非医师医疗保健工作者(包括社区药剂师)作为一种有效的、具有成本效益的医疗服务提供模式。在尼日利亚,尚未探索使用社区药剂师对 CVD 风险因素进行大规模筛查。目的:我们旨在研究药剂师在社区药房进行大规模 CVD 风险因素筛查的可能性。地点:尼日利亚拉各斯。方法:在 2018 年 10 月至 12 月期间,在 10 家社区药房对 889 名看似健康的参与者进行了肥胖、高血压、糖尿病和高胆固醇血症的筛查。使用即时检测模式筛查糖尿病和高胆固醇血症。使用结构化问卷获取参与者的社会人口统计学数据。主要观察指标:超重/肥胖、高血压、糖尿病、高胆固醇血症、吸烟和饮酒的患病率。结果:受试者的平均年龄为 56.8±21.1 岁。大多数(57.4%)为女性。吸烟和饮酒的患病率分别为 4.3%和 26.7%。男性和女性分别有 59.7%和 71.5%超重(BMI≥25kg/m)或肥胖(BMI≥30kg/m)。所有受试者的高血压患病率为 28.2%,男性为 30.9%,女性为 26.3%,p<0.001。使用 BP>130/80mmHg,高血压的患病率为 55.1%。检测到 3%的受试者患有糖尿病,而 45.3%的受试者患有高胆固醇血症。总共有 64.1%的受试者首次被诊断患有 CVD 风险因素。结论:在社区药房进行 CVD 风险因素的机会性筛查是可行的,并且有能力发现以前未被诊断的风险因素。这种基于社区药房的模式可以作为 CVD 一级预防的一种具有成本效益的方法。

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