Department of Orthopedics and Traumatology, Ankara Yildirim Beyazit University Medical Faculty, Ankara Yildirim Beyazit University, 06100, Ankara, Turkey.
Department of Physical Treatment and Rehabilitation, Middle East Technical University Medical Center, 06100, Ankara, Turkey.
Musculoskelet Surg. 2022 Jun;106(2):145-153. doi: 10.1007/s12306-020-00681-9. Epub 2020 Sep 22.
This study aimed to assess the impact of biodegradable polyurethane meniscus scaffold implantation (BPMSI) on muscle strength and balance in comparison with the healthy contralateral knee in patients with irreparable medial meniscus defect.
This observational and prospective case-cohort study was conducted with patients who had irreparable meniscal defects and underwent arthroscopic meniscus scaffold implantation. Surgeries were carried out on the medial meniscus of 16 right and 4 left knees. Visual analog scale (VAS) was used to assess the degree of pain relief. Knee Injury and Osteoarthritis Outcome Score (KOOS) and Lysholm (LYS) score were used to evaluate the functional improvement at weeks 12, 24 and 36. Concentric and eccentric quadriceps and hamstring peak torque (PT) as well as the peak torque-to-body weight (PTB) ratio, anterior-posterior, mediolateral and overall stability indexes were assessed at the same time points.
Twenty male patients with a mean age and body mass index of 32.2 ± 8.8 years and 26.2 ± 4.2 kg/m, respectively, were included in the study. The amount of pain decreased from 7.6 ± 1.5% to 2.9 ± 1.5% at postoperative week 36. Range of motion, Lysholm score and KOOS increased from 87.0 ± 9.5 to 115.0 ± 15.1, 30.8 ± 4.3 to 81.5 ± 5.3 and 37.4 ± 5.3 to 74.1 ± 7.2, respectively. Concentric quadriceps and hamstring peak torque values and peak torque/body weight ratios were improved in the knees that received a meniscus scaffold implant. Anterior/posterior, medial/lateral, and overall stability indexes with or without biofeedback exhibited a slight improvement, which was not statistically significant.
BPMSI led to decreased pain and improved function at postoperative week 36. Although muscle strength almost returned to normal, balance parameters did not recover within 36 weeks after the procedure.
本研究旨在评估生物可降解聚氨酯半月板支架植入（BPMSI）对不可修复内侧半月板缺陷患者的肌肉力量和平衡的影响，并与健侧膝关节进行比较。
本研究为前瞻性观察性病例对照研究，纳入了接受关节镜半月板支架植入术的不可修复半月板缺陷患者。手术在 16 个右侧和 4 个左侧膝关节的内侧半月板上进行。采用视觉模拟评分（VAS）评估疼痛缓解程度。采用膝关节损伤和骨关节炎结果评分（KOOS）和 Lysholm（LYS）评分在 12、24 和 36 周时评估功能改善情况。在相同时间点评估股四头肌和腘绳肌的等速向心和离心峰力矩（PT）以及峰力矩与体重的比值（PTB）、前-后、内-外侧和整体稳定性指数。
研究共纳入 20 名男性患者，平均年龄和体重指数分别为 32.2±8.8 岁和 26.2±4.2kg/m²。术后 36 周时疼痛程度从 7.6±1.5%降至 2.9±1.5%。术后 36 周时关节活动度、Lysholm 评分和 KOOS 评分分别从 87.0±9.5 增加到 115.0±15.1、30.8±4.3 增加到 81.5±5.3 和 37.4±5.3 增加到 74.1±7.2。接受半月板支架植入的膝关节的等速股四头肌和腘绳肌峰力矩值和峰力矩/体重比值均得到改善。有无生物反馈的前-后、内-外侧和整体稳定性指数均略有改善，但无统计学意义。
BPMSI 可在术后 36 周减轻疼痛并改善功能。尽管肌肉力量几乎恢复正常，但平衡参数在术后 36 周内未恢复正常。
