Department of Medical Psychology, Chaohu Clinical Medical College, Anhui Medical University, Hefei 230032, China; Anhui Province Key Laboratory of Cognition and Neuropsychiatric Disorders, Hefei 230032, China; Collaborative Innovation Center for Neuropsychiatric Disorders and Mental Health, Anhui Medical University, Hefei 230032, China.
Department of First Clinical Medical College, Anhui Medical University, Hefei 230032, China.
Neurosci Lett. 2020 Nov 1;738:135396. doi: 10.1016/j.neulet.2020.135396. Epub 2020 Sep 19.
The deficit in emotional face processing is a critical impairment for individuals with high autistic traits. The temporalparietal junction(TPJ) is considered to be closely related to emotional face processing. The aim of this study was to examine the effect of highdefinition transcranial direct current stimulation (HD-tDCS) over the right temporal-parietal junction (rTPJ) on facial emotion processing of individuals with high autistic traits using eye-tracking technology. Twenty-nine participants with high autistic traits completed an eyetracking task (including happy, fearful and neutral faces) before and after five consecutive days of stimulation (anodal or sham). Results showed that anodal HD-tDCS significantly increased fixation time and fixation count in the mouth area, but this effect was not found after the sham stimulation. Moreover, this increased effect of mouth recognition with anodal rTPJ HD-tDCS was shown in both happy and fearful faces, but no remarkable difference was found in neutral faces. These findings suggest that right TPJ anodal HD-tDCS can facilitate emotional face processing in individuals with high autistic traits.
情绪面孔加工缺陷是高自闭症特质个体的严重障碍。颞顶联合区(TPJ)被认为与情绪面孔加工密切相关。本研究旨在使用眼动技术,探讨右颞顶联合区(rTPJ)的高清晰度经颅直流电刺激(HD-tDCS)对高自闭症特质个体的面部情绪处理的影响。29 名具有高自闭症特质的参与者在连续 5 天的刺激(阳极或假刺激)前后完成了眼动任务(包括快乐、恐惧和中性面孔)。结果表明,阳极 HD-tDCS 显著增加了嘴部区域的注视时间和注视次数,但假刺激后没有发现这种效果。此外,阳极 rTPJ HD-tDCS 对口部识别的这种增强效果在快乐和恐惧面孔中都有体现,但在中性面孔中没有发现显著差异。这些发现表明,右 TPJ 阳极 HD-tDCS 可以促进高自闭症特质个体的情绪面孔加工。