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资源有限环境下宫颈癌的外科治疗:来自斯里兰卡国家癌症研究所的一年数据。

Surgical management of cervical cancer in a resource-limited setting: One year of data from the National Cancer Institute, Sri Lanka.

机构信息

Castle Street Hospital for Women, Colombo, Sri Lanka.

Gynaecological Oncology Unit, National Cancer Institute (Apeksha Hospital), Maharagama, Sri Lanka.

出版信息

Int J Gynaecol Obstet. 2021 Jan;152(1):78-81. doi: 10.1002/ijgo.13384. Epub 2020 Oct 13.

Abstract

OBJECTIVE

To evaluate the surgical management of cervical cancer without the use of preoperative pelvic imaging in a resource-limited setting.

METHODS

A retrospective study was carried out using clinical records and the ongoing electronic database at the Gynaecological Oncology Unit, National Cancer Institute (Apeksha Hospital), Maharagama, Sri Lanka. Details regarding the radical hysterectomies carried out from January 1, 2019, to December 31, 2019, were retrospectively studied.

RESULTS

Out of nearly 700 patients with cervical cancer admitted during the year 2019, 57 surgically managed radical hysterectomies were included. Of these, seven cases were ineligible and excluded and 50 cases of radical hysterectomies were included for analysis. Mean age was 53.6 ± 9.5 years and median parity was 3 (range 2-4). Of the cases, 94% were found to have no parametrial involvement showing the success of clinical examination in assessing local tumor spread. Overall, 11 (22.0%) were upstaged due to lymph node metastasis that was statistically significant.

CONCLUSION

Preoperative clinical staging is a practical method in selecting surgically treatable cervical cancer in low- and middle-income countries (LMICs). Combining clinical assessment with comparatively more readily available computed tomography scans could be helpful in triaging patients for treatment of cervical cancer in LMICs.

摘要

目的

在资源有限的环境下,评估不使用术前骨盆影像学检查的宫颈癌手术治疗方法。

方法

对斯里兰卡马哈拉加马国家癌症研究所(Apeksha 医院)妇科肿瘤学系的临床记录和正在进行的电子数据库进行了回顾性研究。回顾性研究了 2019 年 1 月 1 日至 2019 年 12 月 31 日期间进行的根治性子宫切除术的详细信息。

结果

在 2019 年接受治疗的近 700 名宫颈癌患者中,有 57 例接受了手术治疗。其中 7 例因不符合条件而被排除,50 例接受了根治性子宫切除术。平均年龄为 53.6±9.5 岁,中位数孕次为 3(范围 2-4)。在这些病例中,94%的患者没有发生宫旁侵犯,这表明临床检查在评估局部肿瘤扩散方面取得了成功。总的来说,有 11 例(22.0%)因淋巴结转移而被升级,这具有统计学意义。

结论

术前临床分期是选择可手术治疗的中低收入国家(LMICs)宫颈癌的一种实用方法。将临床评估与相对更容易获得的计算机断层扫描相结合,可能有助于对 LMICs 的宫颈癌患者进行治疗。

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