Yee J, McAllister C K
South Med J. 1987 Jun;80(6):753-7. doi: 10.1097/00007611-198706000-00020.
Osler's nodes are classic lesions strongly associated with infective endocarditis. Osler's original description placed them as a frequent finding (70%) in cases of endocarditis. Recent literature, however, has infrequently described these lesions, which in general are no longer found to be useful. We review the clinical syndromes of infective endocarditis and their association with these lesions. We also review the pathogenesis of the lesion that currently supports the embolic nature of Osler's nodes. Osler's nodes are helpful clues if they appear in patients with infective endocarditis, and biopsy and culture of the lesion may provide an etiologic diagnosis.
奥斯勒结节是与感染性心内膜炎密切相关的典型病变。奥斯勒最初的描述表明，它们在感染性心内膜炎病例中是常见表现（70%）。然而，近期文献对这些病变的描述较少，总体而言它们已不再被认为有用。我们回顾了感染性心内膜炎的临床综合征及其与这些病变的关联。我们还回顾了目前支持奥斯勒结节栓塞性质的病变发病机制。如果奥斯勒结节出现在感染性心内膜炎患者中，它们是有用的线索，对病变进行活检和培养可能有助于做出病因诊断。
