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髋部骨折患者多状态模型短期独立恢复的预后因素。

Prognostic Factors for Short-term Recovery of Independence in a Multistate Model for Patients With a Hip Fracture.

机构信息

Department of Public Health and Primary Care, Leiden University Medical Center, Leiden, the Netherlands.

Department of Public Health and Primary Care, Leiden University Medical Center, Leiden, the Netherlands.

出版信息

J Am Med Dir Assoc. 2021 Jun;22(6):1307-1312. doi: 10.1016/j.jamda.2020.08.006. Epub 2020 Sep 19.

Abstract

OBJECTIVES

This study investigates the transitions of community-dwelling patients with a proximal femoral fracture towards recovery of independence using multistate modeling. The prognostic value of factors affecting the short-term rate of recovery of independence in activities of daily living was assessed for the resilient portion of the population.

DESIGN

An inception cohort was recruited between 2016 and 2019.

SETTING AND PARTICIPANTS

Only community-dwelling older patients admitted with a proximal femoral fracture were included.

MEASURES

Follow-up was performed at 6 weeks and 3 months, when the patients' living situation and level of independence were recorded. Multistate modeling was used to study the transition rates of the population through prespecified states of the recovery process. Using this model, prognostic factors for the recovery of independence were identified for resilient patients (defined as those patients who managed to return home at any point in the follow-up after discharge).

RESULTS

A total of 558 patients were included, and 218 (40.9%) recovered to prefracture levels of independence. Of the resilient patients, 20.7% were discharged home directly, and 79.3% via a rehabilitation home. In this patient group, a more favorable American Society of Anesthesiologists classification, better prefracture mobility, and the absence of a prefracture fear of falling were statistically significantly associated with a successful recovery. A low level of prefracture independence was inversely associated, meaning that patients with a low level of prefracture independence had a higher chance of successful recovery.

CONCLUSIONS AND IMPLICATIONS

This study identified 4 factors with an independent prognostic value for the recovery of independence in resilient patients after a proximal femoral fracture. These factors could be used to construct clinical profiles that contribute to the assessment of the patient's post-acute care needs and recovery capacity. In addition, multistate modeling has been shown to be an effective and versatile tool in the study of recovery prognostics.

摘要

目的

本研究采用多状态模型探讨了社区居住的股骨近端骨折患者向日常生活活动独立性恢复的转变。评估了对人群中具有弹性部分短期恢复独立性的短期率有影响的因素的预后价值。

设计

在 2016 年至 2019 年期间招募了一个发病队列。

设置和参与者

仅包括因股骨近端骨折而住院的社区居住的老年患者。

测量

在 6 周和 3 个月时进行随访,记录患者的生活状况和独立性水平。使用多状态模型研究人群通过预先指定的恢复过程状态的转移率。使用该模型,确定了具有弹性的患者(定义为在出院后随访的任何时间都能够返回家中的患者)恢复独立性的预后因素。

结果

共纳入 558 例患者,其中 218 例(40.9%)恢复到骨折前的独立水平。在具有弹性的患者中,有 20.7%的患者直接出院回家,有 79.3%的患者出院回家需要康复。在这个患者组中,更好的美国麻醉医师协会分类、更好的骨折前移动能力以及骨折前没有跌倒恐惧与成功恢复具有统计学显著相关性。骨折前的独立性水平较低与成功恢复呈负相关,这意味着骨折前独立性水平较低的患者成功恢复的机会更高。

结论和意义

本研究确定了 4 个与股骨近端骨折后具有弹性的患者恢复独立性具有独立预后价值的因素。这些因素可用于构建有助于评估患者急性后护理需求和恢复能力的临床概况。此外,多状态模型已被证明是研究恢复预后的有效和多功能工具。

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