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13 岁儿童甲床撕脱伤的脱细胞真皮基质重建。

Acellular dermal matrix reconstruction of a nail bed avulsion in a 13-year-old child.

机构信息

Department of Plastic and Reconstructive Surgery, Queen Elizabeth Hospital, Birmingham, UK

Department of Plastic and Reconstructive Surgery, Guy's and Saint Thomas' NHS Foundation Trust, London, UK.

出版信息

BMJ Case Rep. 2020 Sep 22;13(9):e236253. doi: 10.1136/bcr-2020-236253.

DOI:10.1136/bcr-2020-236253
PMID:32963043
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7509955/
Abstract

Nail bed avulsion injuries often require reconstruction, particularly in cases where the avulsed fragment is lost. We describe a simple way to reconstruct a large nail bed defect, with no donor site. A 13-year-old boy with a hypoplastic left heart and autism accidentally sustained a left little distal phalanx injury with an avulsion of 60% of the nail bed, exposing the distal phalanx. This boy had a history of poor compliance, qualifying the need to find a technique that would minimise operative time and dressing changes. As such, it was elected to use an acellular dermal matrix (ADM) (Matriderm) as a one-step reconstruction. Signs of vascularisation of the ADM were noted at 2 weeks, and 3-month follow-up demonstrated integration, with normal nail growth. We found that Matriderm was able to support the regeneration of a full thickness wound in a simple one-step procedure.

摘要

甲床撕脱伤常需要重建,特别是撕脱的碎片丢失的情况下。我们描述了一种简单的方法来重建一个大的甲床缺损,且无需供区。一名 13 岁男孩患有左心发育不全和自闭症,意外地遭受了左手小远节指骨损伤,甲床撕脱 60%,远节指骨外露。这个男孩既往依从性差,需要找到一种可以尽量减少手术时间和换药次数的技术。因此,我们选择使用脱细胞真皮基质 (ADM) (Matriderm) 作为一步法重建。在第 2 周时观察到 ADM 的血管化迹象,3 个月的随访显示了整合,有正常的指甲生长。我们发现 Matriderm 能够在一个简单的一步法中支持全层伤口的再生。

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引用本文的文献

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Acellular dermal matrix in reconstructive surgery: Applications, benefits, and cost.重建手术中的脱细胞真皮基质:应用、益处及成本。
Front Transplant. 2023 Mar 10;2:1133806. doi: 10.3389/frtra.2023.1133806. eCollection 2023.
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Plast Reconstr Surg Glob Open. 2024 Jan 24;12(1):e5551. doi: 10.1097/GOX.0000000000005551. eCollection 2024 Jan.

本文引用的文献

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Improving theatre turnaround time.缩短手术室周转时间。
BMJ Qual Improv Rep. 2017 Feb 10;6(1). doi: 10.1136/bmjquality.u219831.w8131. eCollection 2017.
2
Nail Bed Reconstruction Using Single-Layer Bovine Acellular Dermal Matrix.使用单层牛脱细胞真皮基质进行甲床重建。
J Hand Surg Am. 2017 Jan;42(1):e67-e74. doi: 10.1016/j.jhsa.2016.10.010.
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Systematic review and critical appraisal of the impact of acellular dermal matrix use on the outcomes of implant-based breast reconstruction.系统评价和关键评估脱细胞真皮基质在基于植入物的乳房重建结果中的影响。
Br J Surg. 2015 Aug;102(9):1010-25. doi: 10.1002/bjs.9804. Epub 2015 Jun 24.
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The use of matriderm and autologous skin graft in the treatment of full thickness skin defects.基质胶与自体皮移植在全层皮肤缺损治疗中的应用。
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