Kamble Prathamesh Haridas, Dubhashi Siddharth Pramod
Department of Physiology, All India Institute of Medical Sciences, Nagpur, India.
Department of General Surgery, All India Institute of Medical Sciences (AIIMS), MIHAN, Nagpur, India.
Pan Afr Med J. 2020 Jul 22;36:206. doi: 10.11604/pamj.2020.36.206.23977. eCollection 2020.
The intense global efforts are directed towards development of vaccines to halt the COVID-19 virus pandemic. There are 160 candidate vaccines under clinical trials across the world using different molecular targets and techniques. This race for the vaccine has several challenges and ethical issues like compressed timelines, generation and proper management of resources and finances, risks to the participating volunteers due to curtailed research trial processes, geopolitical contentions, misinformation through social media and parallel race with drugs. We feel that the fundamental principles of ethics: autonomy, beneficence, non-maleficence and justice should not be violated in this hastened vaccine development process. We recommend constitute a Consortium on a global platform to formulate, provide and monitor a comprehensive ethical umbrella to the process of vaccine development.
全球正在全力以赴研发疫苗以遏制新冠病毒大流行。全球有160种候选疫苗正处于临床试验阶段，采用了不同的分子靶点和技术。这场疫苗竞赛面临诸多挑战和伦理问题，比如时间紧迫、资源和资金的产生与妥善管理、由于研究试验流程缩短给参与试验的志愿者带来的风险、地缘政治争端、社交媒体上的错误信息以及与药物研发的并行竞争。我们认为，在这一加速的疫苗研发过程中，伦理的基本原则：自主性、行善、不伤害和公正不应被违背。我们建议在全球平台上组建一个联盟，为疫苗研发过程制定、提供并监督全面的伦理保障。
