Knežić Matija, Bekafigo Irena Seili, Roganović Jelena, Hadžisejdić Ita, Jonjić Nives
University of Rijeka, Faculty of Medicine, Braće Branchetta 20/1, 51000 Rijeka, Croatia.
Department of Pathology and Cytology, Clinical Hospital Center Rijeka, Cambierieva 17, 51000 Rijeka, Croatia.
Case Rep Pathol. 2020 Sep 8;2020:5606391. doi: 10.1155/2020/5606391. eCollection 2020.
Burkitt lymphoma (BL) is a highly aggressive but potentially curable disease as long as adequately treated within due time. BL may occur primarily and exclusively in the bone marrow as a form of peripheral and extranodal disease. BL cases with isolated bone marrow involvement are challenging in regard to a prompt diagnostic process. We report a case of a sporadic extranodal subtype of isolated bone marrow BL in an 11-year-old boy. Bone marrow aspiration and biopsy, flow cytometry, and immunohistochemistry along with cytogenetics are compulsory in order to achieve the adequate diagnosis.
伯基特淋巴瘤（BL）是一种高度侵袭性但只要在适当时间内得到充分治疗就有可能治愈的疾病。BL可能主要且仅在骨髓中作为外周和结外疾病的一种形式出现。孤立性骨髓受累的BL病例在快速诊断过程方面具有挑战性。我们报告了一例11岁男孩散发的孤立性骨髓BL结外亚型病例。为了做出充分诊断，骨髓穿刺和活检、流式细胞术、免疫组织化学以及细胞遗传学检查是必不可少的。
