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老年人抑郁症与认知障碍之间的关系:一项横断面研究。

Relationship between Depression and Cognitive Impairment among Elderly: A Cross-sectional Study.

作者信息

Aajami Zahra, Kazazi Leila, Toroski Mahdi, Bahrami Malihe, Borhaninejad Vahidreza

机构信息

Department of Pharmacoeconomics and Pharmaceutical Administration, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran.

Iranian Research Center on Ageing, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran.

出版信息

J Caring Sci. 2020 Aug 18;9(3):148-153. doi: 10.34172/jcs.2020.022. eCollection 2020 Aug.

Abstract

Depression and cognitive impairment are common mental health problems among elderly, although few studies have examined their co-occurrence in aging population. So the aim of this study was to determine the relationship between depression and cognitive impairment in older adults. This cross-sectional population-based study was conducted on 506 older adults were presented to the health centers of the municipality of Tehran, Iran. Data were collected using the sociodemographic questionnaire, Mini-Mental State Examination (MMSE) and Geriatric Depression Scale (GDS). Data were analyzed by using SPSS-17 with correlation analysis and logistic regression. The mean age of the participants was 65.71 years. Older people (>75 years) had more twice risk (95% CI: 1.01-4.90) for cognitive dysfunction. There was a significant correlation between MMSE and GDS. Elderly with collegiate education had 85% (95% CI: 0.1-0.5) and employed elderly had 56% (95% CI: 0.04-0.74) lower risk for cognitive dysfunction. Elderly with severe depression had twice risk (95% CI: 1.41-4.8) for cognitive dysfunction. Findings suggest there is a relationship between depression and cognitive impairment among the elderly. These findings emphasis on assessing cognitive impairment and depression in geriatric assessment in elderly.

摘要

抑郁症和认知障碍是老年人常见的心理健康问题,尽管很少有研究探讨它们在老年人群中的共现情况。因此,本研究的目的是确定老年人抑郁症与认知障碍之间的关系。这项基于人群的横断面研究对506名前往伊朗德黑兰市卫生中心就诊的老年人进行。使用社会人口学问卷、简易精神状态检查表(MMSE)和老年抑郁量表(GDS)收集数据。使用SPSS - 17进行数据分析,采用相关分析和逻辑回归。参与者的平均年龄为65.71岁。年龄较大的人(>75岁)出现认知功能障碍的风险高出两倍(95%置信区间:1.01 - 4.90)。MMSE和GDS之间存在显著相关性。受过大学教育的老年人出现认知功能障碍的风险降低85%(95%置信区间:0.1 - 0.5),就业的老年人风险降低56%(95%置信区间:0.04 - 0.74)。患有严重抑郁症的老年人出现认知功能障碍的风险高出两倍(95%置信区间:1.41 - 4.8)。研究结果表明老年人抑郁症与认知障碍之间存在关联。这些发现强调在老年评估中对老年人认知障碍和抑郁症进行评估。

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