Department of Clinical Immunology and Transfusion Medicine, Uppsala University Hospital, Uppsala, Sweden.
Clinical Epidemiology Division, Department of Medicine, Solna, Karolinska Institutet, Stockholm, Sweden.
Transfusion. 2020 Nov;60(11):2529-2536. doi: 10.1111/trf.16092. Epub 2020 Sep 23.
Transfusion patterns in Sweden have not been characterized on a nationwide level.
We conducted a nationwide descriptive cohort study in Sweden from 2008 to 2017. Data on blood donors, donations, component manufacture, transfusions, and transfused patients were extracted from Swedish portion of the Scandinavian Donations and Transfusions (SCANDAT3-S) database.
A total of 708 436 patients received 5 587 684 red cell, plasma, or platelet transfusions during the study period. The age-standardized transfusion rate decreased markedly during the study period for red cell units (from 53 to 39 units/1000 persons) and plasma units (from 11 to 4.9 units/1000 persons), but remained relatively constant for platelet concentrates. The transfusion rate was 30%-40% higher in males than in females in the first year of life, and higher in males over 45 years than in females. Between age 20 and 45, the majority of red cells were transfused to female patients with obstetric indications, whereas trauma was the predominant indication for male contemporaries. In females over 80 years, the largest proportion of red cells were administered due to trauma. Overall, hematological patients received 36% of all platelet units. There were large regional differences in transfusion rates for red cell units, ranging from less than 30 to greater than 60/1000 persons.
Transfusion rates in Sweden remain high but have decreased strikingly during the study period - with the exception of platelet transfusions. Based on the available data, it is difficult to draw firm conclusions about whether transfusion rates can be further reduced.
瑞典的输血模式尚未在全国范围内进行描述。
我们在 2008 年至 2017 年期间在瑞典进行了一项全国性描述性队列研究。从斯堪的纳维亚献血和输血（SCANDAT3-S）数据库的瑞典部分提取了关于献血者、献血、成分制造、输血和输血患者的数据。
在研究期间，共有 708436 名患者接受了 5587684 单位红细胞、血浆或血小板输血。在研究期间，红细胞单位（从 53 降至 39 单位/1000 人）和血浆单位（从 11 降至 4.9 单位/1000 人）的年龄标准化输血率显著下降，但血小板浓缩物的输血率相对保持不变。在生命的第一年，男性的输血率比女性高 30%-40%，45 岁以上的男性比女性高。在 20 至 45 岁之间，大多数红细胞输给了有产科指征的女性患者，而创伤是男性同期的主要指征。在 80 岁以上的女性中，由于创伤，输注了最大比例的红细胞。总体而言，血液系统患者接受了所有血小板单位的 36%。红细胞单位的输血率存在较大的地区差异，范围从不到 30 至超过 60/1000 人。
瑞典的输血率仍然很高，但在研究期间显著下降-除了血小板输血。根据现有数据，很难确定输血率是否可以进一步降低。
