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[用于移植的多器官获取]

[Multiple-organ procurement for transplantation].

作者信息

Bricard H, Leroy G, Trovero C, Buteux G, Samba D, Suisse A, Tartière J, Auger E, Quesnel J, Ségol P

出版信息

Ann Fr Anesth Reanim. 1987;6(2):133-41. doi: 10.1016/s0750-7658(87)80121-1.

DOI:10.1016/s0750-7658(87)80121-1
PMID:3296869
Abstract

In the last few years, the tremendous growth of clinical transplantations has greatly increased the need for grafts. Combined heart, liver and kidney harvesting in a same donor could provide an answer. The results are presented of multiple organ retrieval (MOR) carried out in an University hospital located in an area with 1,350,000 inhabitants. In addition to the usual problems of donor maintenance and legal aspects, it was necessary to carry out a specific work-up for each organ to be harvested. The job of the local coordinator was extremely important in the search for potential recipients and the organization of the procedure (time-table, air transport) in order to give optimal conditions. The priority given to retrieving the heart and in situ cooling of the liver and kidneys guaranteed the good quality of the harvested organs. Over a period of three years, 28 MOR have been carried out. Of the 94 organs harvested, 88 were transplanted in France or another European country (49 kidneys, 23 hearts, 16 livers); 75 are still functioning (47 kidneys, 19 hearts, 9 livers). As a result of this experience, and taking into account the need for organs, all brain dead patients should be considered as potential multiple organ donors, and not just as kidney donors. The intervention of several teams, often quite distant from the site of retrieval, requires careful planning. The surgical procedure, even when performed by a trained team, is often complex, perfect synchronization of the surgical steps of the operation being the most important point.(ABSTRACT TRUNCATED AT 250 WORDS)

摘要

在过去几年中,临床移植手术的迅猛发展极大地增加了对移植物的需求。在同一个供体身上联合摘取心脏、肝脏和肾脏或许能解决这一问题。本文呈现了在一所位于拥有135万居民地区的大学医院开展的多器官获取(MOR)结果。除了供体维护和法律方面的常见问题外,有必要对每个待摘取器官进行特定的检查。当地协调员的工作在寻找潜在受者以及组织手术流程(时间表、航空运输)方面极为重要,以便提供最佳条件。优先摘取心脏以及对肝脏和肾脏进行原位冷却确保了所摘取器官的良好质量。在三年时间里,共进行了28例多器官获取手术。在所摘取的94个器官中,88个在法国或其他欧洲国家进行了移植(49个肾脏、23颗心脏、16个肝脏);75个仍在发挥功能(47个肾脏、19颗心脏、9个肝脏)。基于这一经验,并考虑到对器官的需求,所有脑死亡患者都应被视为潜在的多器官供体,而不仅仅是肾脏供体。多个团队的介入,这些团队往往离获取地点较远,这需要精心规划。手术过程即便由训练有素的团队进行,通常也很复杂,手术步骤的完美同步是最为关键的一点。(摘要截选至250词)

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