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原发性右心室良性肿瘤切除术的 10 年随访:10 年手术经验。

Long-term follow-up of resection of primary benign right ventricular tumours: a 10-year surgical experience.

机构信息

Structural Heart Disease Centre, National Centre for Cardiovascular Disease and Fuwai Hospital, Peking Union Medical College, Beijing, China.

National Centre for Cardiovascular Disease and Fuwai Hospital, Peking Union Medical College, Beijing, China.

出版信息

Ann R Coll Surg Engl. 2021 Jan;103(1):53-58. doi: 10.1308/rcsann.2020.0200. Epub 2020 Sep 24.

Abstract

INTRODUCTION

Primary benign right ventricular tumours are rare. They can cause significant mortality without appropriate and timely treatment. We investigated surgical treatment and survival characteristics for right ventricular tumours.

MATERIALS AND METHODS

From 2007 to 2017, 21 patients with primary benign right ventricular tumours who underwent tumour resection were retrospectively reviewed. Clinical findings and follow-up results were analysed.

RESULTS

Thirteen men and eight women were enrolled, with a mean age of 42.3 ± 15.3 years. The most frequent histotypes were myxoma, haemangioma and papillary fibroelastoma. Eight patients underwent concomitant tricuspid valvuloplasty and one had tricuspid valve replacement. No major adverse events or death occurred during the perioperative period. One patient with haemangioma underwent partial tumour resection; however, the tumour regressed gradually during follow-up. Within the 10-year follow-up period (mean 4.8 ± 2.6 years), the recurrence-free and overall survival rates were 81.0% and 85.7%, respectively.

CONCLUSIONS

Tumour resection for primary benign right ventricular tumours is safe and effective, and has a good prognosis. Tricuspid valvuloplasty or tricuspid valve replacement may be necessary for the resection of right ventricular tumours to improve the haemodynamics. Haemangiomas naturally undergo spontaneous regression.

摘要

简介

原发性良性右心室肿瘤较为罕见。如果得不到适当和及时的治疗,它们可能导致严重的死亡率。我们研究了右心室肿瘤的手术治疗和生存特点。

材料和方法

2007 年至 2017 年,我们回顾性分析了 21 例接受肿瘤切除术的原发性良性右心室肿瘤患者。分析了临床发现和随访结果。

结果

共纳入 13 名男性和 8 名女性患者,平均年龄为 42.3±15.3 岁。最常见的组织学类型是黏液瘤、血管瘤和乳头状纤维弹性瘤。8 例患者同时行三尖瓣成形术,1 例患者行三尖瓣置换术。围手术期无重大不良事件或死亡发生。1 例血管瘤患者行部分肿瘤切除术,但在随访过程中肿瘤逐渐消退。在 10 年的随访期(平均 4.8±2.6 年)内,无复发生存率和总体生存率分别为 81.0%和 85.7%。

结论

肿瘤切除术治疗原发性良性右心室肿瘤安全有效,预后良好。为改善右心室肿瘤切除后的血液动力学,可能需要行三尖瓣成形术或三尖瓣置换术。血管瘤可自然发生退行性变。

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