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通过间接荧光抗体试验确定的马来西亚原住民(奥朗阿斯利人)中的疟疾流行情况。

Malaria endemicity among Orang Asli (Malaysian aborigines) as determined by indirect fluorescent antibody tests.

作者信息

Thomas V, Dissanaike A S

出版信息

Am J Trop Med Hyg. 1977 Jul;26(4):602-6. doi: 10.4269/ajtmh.1977.26.602.

Abstract

Fluorescent antibodies were detected in 89% of 288 Orang Asli (Malaysian aborigines) with Plasmodium falciparum antigen and in 62% with P. brasilianum (for P. malariae) antigen. Blood films from 18 donors were positive for P. falciparum; 2 of them had mixed infection with P. vivax. Seven of the P. falciparum-positive blood films were from children in the 2- to 9-year age group. Of 17 sera from cord blood, 16 had significant levels of P. falciparum antibody and 14 of P. malariae antibody, the levels being the same as those of the mothers. None of these babies had congenital malaria. A higher percentage of male donors reacted to both antigens. There was an age dependent increase in the number positive and the maximum titers.

摘要

在288名患有恶性疟原虫抗原的奥朗阿斯利人(马来西亚原住民)中,89%检测到荧光抗体;在患有巴西疟原虫(间日疟原虫)抗原的人中,62%检测到荧光抗体。18名献血者的血涂片恶性疟原虫呈阳性;其中2人同时感染间日疟原虫。7份恶性疟原虫阳性血涂片来自2至9岁年龄组的儿童。在17份脐带血血清中,16份有显著水平的恶性疟原虫抗体,14份有间日疟原虫抗体,其水平与母亲相同。这些婴儿均无先天性疟疾。较高比例的男性献血者对两种抗原均有反应。阳性数量和最高滴度随年龄增长而增加。

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