Ubayama Y
Gan To Kagaku Ryoho. 1987 May;14(5 Pt 2):1597-602.
Liposarcoma is one of the most common soft tissue sarcomas, ranking with rhabdomyosarcoma and malignant fibrous histiocytoma. We have treated 47 cases of liposarcoma, comprising 35 males and 12 females ranging in age from 22 to 86 years, with a median age of 56 years. The most common site of primary tumor was the thigh, the most common primary tumor stage by the UICC classification was T2, and the most common histological subtype by the WHO classification was myxoid type. Xerography, CT and angiography are useful forms of examination for diagnosis before surgery. Naked eye findings of the tumor often show a lobular or nodular growth pattern. Surgical therapy for the primary tumor, especially curative wide resection (by the method of Kawaguchi, et al.) is most effective for preventing local recurrence. Radiotherapy is not as effective as for rhabdomyosarcoma and chemotherapy should be applied for occult micro-metastases. Ten of the 47 cases died due to distant metastases and the 5 year survival rate was 76.2%.
脂肪肉瘤是最常见的软组织肉瘤之一，与横纹肌肉瘤和恶性纤维组织细胞瘤并列。我们共治疗了47例脂肪肉瘤患者，其中男性35例，女性12例，年龄在22岁至86岁之间，中位年龄为56岁。原发肿瘤最常见的部位是大腿，按照国际抗癌联盟（UICC）分类，最常见的原发肿瘤分期为T2，按照世界卫生组织（WHO）分类，最常见的组织学亚型为黏液样型。X线摄影、CT和血管造影是术前诊断的有用检查方式。肿瘤的肉眼表现常呈小叶状或结节状生长模式。对原发肿瘤的手术治疗，尤其是根治性广泛切除（采用川口等人的方法）对预防局部复发最为有效。放疗不如对横纹肌肉瘤有效，化疗应针对隐匿性微转移应用。47例中有10例死于远处转移，5年生存率为76.2%。
