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坚韧性、C-反应蛋白与前战俘端粒长度之间的关系。

Associations between hardiness, C-reactive protein, and telomere length among former prisoners of war.

机构信息

Department of Behavioral Sciences and Psychology.

School of Psychology.

出版信息

Health Psychol. 2020 Nov;39(11):1007-1012. doi: 10.1037/hea0001030. Epub 2020 Sep 24.

DOI:10.1037/hea0001030
PMID:32969697
Abstract

BACKGROUND

War captivity and posttraumatic stress disorder (PTSD) are known to be associated with several poor health outcomes of an accelerated aging process. However, the contribution of personality protective factors to this phenomenon are rarely studied. The present 24-year prospective study examined associations between psychological hardiness and three health outcomes: C-reactive protein (CRP) levels, metabolic syndrome (MetS), and telomere length (TL).

METHOD

Eighty-eight Israeli former prisoners of war (ex-POWs) were assessed 18 (T1) and 42 (T2) years after repatriation. Data on hardiness was collected at T1 while leukocyte TL, CRP, and MetS data was collected 42 years after the war.

RESULTS

While adjusting for age, body mass index (BMI), self-rated health, depressive and PTSD symptoms at T2, higher levels of hardiness at T1 predicted decreased CRP and longer TL at T2.

CONCLUSIONS

Long-term health vulnerabilities of traumatized ex-POWs are manifested in an accelerated aging process and cellular senescence. Raising awareness of the importance of protective factors such as veterans' hardiness might be associated with improving their longevity and well-being. (PsycInfo Database Record (c) 2020 APA, all rights reserved).

摘要

背景

战争俘虏和创伤后应激障碍(PTSD)已知与加速衰老过程中的几种不良健康后果有关。然而,很少有研究探讨人格保护因素对此现象的贡献。本项为期 24 年的前瞻性研究检验了心理坚韧与三种健康结果之间的关系:C 反应蛋白(CRP)水平、代谢综合征(MetS)和端粒长度(TL)。

方法

对 88 名以色列前战俘(前战俘)进行了评估,分别在遣返后 18 年(T1)和 42 年(T2)进行。T1 时收集了坚韧的数据,而白细胞 TL、CRP 和 MetS 数据是在战后 42 年收集的。

结果

在调整 T2 时的年龄、体重指数(BMI)、自我报告的健康状况、抑郁和 PTSD 症状后,T1 时较高的坚韧水平预测 T2 时 CRP 降低和 TL 延长。

结论

创伤后前战俘的长期健康脆弱性表现为加速衰老过程和细胞衰老。提高对退伍军人坚韧等保护因素的重要性的认识,可能有助于改善他们的寿命和健康状况。(PsycInfo 数据库记录(c)2020 APA,保留所有权利)。

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