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干血斑样本中 SARS-CoV-2 特异性抗体的灵敏检测

Sensitive Detection of SARS-CoV-2-Specific Antibodies in Dried Blood Spot Samples.

出版信息

Emerg Infect Dis. 2020 Dec;26(12):2970-2973. doi: 10.3201/eid2612.203309. Epub 2020 Sep 24.

DOI:10.3201/eid2612.203309
PMID:32969788
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7706975/
Abstract

Dried blood spot (DBS) samples can be used for the detection of severe acute respiratory syndrome coronavirus 2 spike antibodies. DBS sampling is comparable to matched serum samples with a relative 98.1% sensitivity and 100% specificity. Thus, DBS sampling offers an alternative for population-wide serologic testing in the coronavirus pandemic.

摘要

干血斑（DBS）样本可用于检测严重急性呼吸综合征冠状病毒 2 刺突抗体。DBS 采样与匹配的血清样本具有可比性，相对灵敏度为 98.1%，特异性为 100%。因此，在冠状病毒大流行期间，DBS 采样为全人群血清学检测提供了一种替代方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bb73/7706975/6b5483e1165d/20-3309-F2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bb73/7706975/7ae1effe7820/20-3309-F1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bb73/7706975/6b5483e1165d/20-3309-F2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bb73/7706975/7ae1effe7820/20-3309-F1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bb73/7706975/6b5483e1165d/20-3309-F2.jpg

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