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曼氏血吸虫病患者肾抗血吸虫抗体的洗脱

Elution of renal antischistosome antibodies in human schistosomiasis mansoni.

作者信息

Moriearty P L, Brito E

出版信息

Am J Trop Med Hyg. 1977 Jul;26(4):717-22. doi: 10.4269/ajtmh.1977.26.717.

DOI:10.4269/ajtmh.1977.26.717
PMID:329698
Abstract

Elution of complexed immunoglobulins was carried out in renal tissue obtained at autopsy from schistosomiasis mansoni and control cases. Substantial amounts of IgG were found in acid eluates of 2 of 5 schistosomiasis cases and 2 of 3 controls. The IgG from schistosomiasis cases produced specific indirect immunofluorescence reactions in gut and tegument of sections of adult Schistosoma mansoni; no reactivity was present against egg granulomas, cercariae, or mouse liver tissue. Control case eluates produced no fluorescence with S. mansoni antigens.

摘要

在对曼氏血吸虫病患者及对照病例尸检获取的肾组织中进行复合免疫球蛋白的洗脱。在5例血吸虫病患者中的2例以及3例对照中的2例的酸性洗脱液中发现了大量IgG。来自血吸虫病病例的IgG在曼氏血吸虫成虫切片的肠道和体表产生了特异性间接免疫荧光反应；对虫卵肉芽肿、尾蚴或小鼠肝组织无反应性。对照病例的洗脱液与曼氏血吸虫抗原未产生荧光。

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