Stem Cell Club, Toronto, ON, Canada.
Faculty of Medicine, University of British Columbia, Vancouver, BC, Canada.
Vox Sang. 2021 Feb;116(2):239-248. doi: 10.1111/vox.13010. Epub 2020 Sep 24.
Diagrams which allow potential unrelated stem cell donors to visualize the stem cell collection process were hypothesized to support the recruitment and education of committed stem cell donors.
A series of bone marrow and peripheral blood stem cell collection procedure diagrams were developed, featuring young adult male donors of varied ethnic backgrounds. Post-implementation, surveys were conducted to evaluate stakeholder perspective on the diagrams' utility. A quality improvement project was conducted at five stem cell drives from 2017 to 2018 at which recruiters did or did not show the diagrams to potential donors. Following the drives, registrants were invited to complete a survey exploring their experience, knowledge and attitude towards donation.
The diagrams were implemented in Canada in 07/2016. Of 293 participating registrants (24·7% non-Caucasian males) recruited at five drives between 2017 and 2018, 76% (n = 197) were shown the diagrams. Participants who were shown the diagrams were significantly more likely to report that the recruiters appeared very knowledgeable (89% vs. 76%, P = 0·019) and to report improved self-reported knowledge of stem cell donation (P = 0·010) compared to participants not shown the diagram. Data are also shown demonstrating that stakeholders in donor recruitment used and valued the diagrams and that use of the diagrams was associated with improved donor recruitment outcomes in Canada.
This report is the first evaluation of stem cell collection diagrams in the literature. The diagrams are relevant to donor registries, recruitment organizations and transplant centres worldwide, and their use may support efforts to educate and recruit committed, ethnically diverse donors.
假设允许潜在的无关干细胞供者可视化干细胞采集过程的图表能够支持承诺的干细胞供者的招募和教育。
开发了一系列骨髓和外周血干细胞采集程序图，以不同种族背景的年轻成年男性供者为特色。实施后，进行了调查以评估利益相关者对图表实用性的看法。在 2017 年至 2018 年期间，在五个干细胞采集活动中进行了一项质量改进项目，招募者在这些活动中向潜在供者展示或不展示图表。在这些活动之后，邀请注册者完成一项调查，探索他们对捐赠的经验、知识和态度。
这些图表于 2016 年 7 月在加拿大实施。在 2017 年至 2018 年期间的五个采集活动中，有 293 名参与者（24.7%为非白种男性）参与了注册，其中 76%（n=197）展示了图表。与未展示图表的参与者相比，展示图表的参与者更有可能报告招募者看起来非常有知识（89%比 76%，P=0.019），并报告自己对干细胞捐赠的知识有所提高（P=0.010）。还显示的数据表明，供者招募中的利益相关者使用并重视图表，并且使用图表与在加拿大提高供者招募结果相关。
这是文献中首次对干细胞采集图表进行评估。这些图表与供者注册处、招募组织和移植中心在全球范围内相关，其使用可能有助于教育和招募承诺的、种族多样化的供者。
