Arch Suicide Res. 2022 Apr-Jun;26(2):656-676. doi: 10.1080/13811118.2020.1820411. Epub 2020 Sep 24.
Although suicide risk is relevant in First Episode Schizophrenia (FES), little data are reported on suicidal ideation and its longitudinal stability. Aim of this study was: (1) to evaluate incidence rates of suicide attempts, completed suicide and suicidal thinking in FES patients at baseline and along a 24-month follow-up period, (2) to investigate any relevant association of baseline suicidal ideation with psychopathology, and (3) to longitudinally monitor suicidal thinking during the 2-years of follow-up. Participants ( = 149; age = 12-35 years) were assessed with the Brief Psychiatric Rating Scale (BPRS) and the Positive and Negative Syndrome Scale. FES participants showed a 40.8% percentage of baseline suicidal ideation (i.e., BPRS item 4 cutoff score of ≥3) and a 2-year cumulative incidence rate of attempted suicide of 6.1%. One completed suicide (0.7%) was also found during the follow-up. Baseline suicidal ideation was positively correlated with depression and negatively correlated with younger age. These results support a routine monitoring of suicide risk in this young population at the point of entry into early intervention services.
尽管自杀风险在首发精神分裂症（FES）中很重要，但关于自杀意念及其纵向稳定性的报道很少。本研究的目的是：（1）评估 FES 患者在基线和 24 个月随访期间自杀企图、自杀死亡和自杀意念的发生率；（2）探讨基线自杀意念与精神病理学的任何相关关联；（3）在 2 年随访期间纵向监测自杀意念。参与者（ = 149；年龄为 12-35 岁）接受了简明精神病评定量表（BPRS）和阳性和阴性综合征量表的评估。FES 参与者的基线自杀意念率为 40.8%（即 BPRS 项目 4 的截止得分≥3），2 年累积自杀企图率为 6.1%。在随访期间还发现了 1 例自杀死亡（0.7%）。基线自杀意念与抑郁呈正相关，与年龄较小呈负相关。这些结果支持在早期干预服务的初始阶段，对这一年轻人群的自杀风险进行常规监测。
