Yildirim Mustafa, Baykara Murat
From the Department of Radiology, Elaziğ Fethi Sekin City Hospital.
Department of Radiology, Firat Faculty of Medicine, Firat University Hospital, Elazig, Turkey.
J Comput Assist Tomogr. 2020 Nov/Dec;44(6):953-955. doi: 10.1097/RCT.0000000000001086.
Metastasis and multiple myeloma are common malignant bone marrow lesions. It may be difficult to distinguish because of similar imaging findings. The purpose of this study was to determine the value of histogram analysis on the computed tomography imaging.
Twenty-three patients with primary tumor and 23 patients with multiple myeloma were included in the study. All patients had lytic bone lesions on the thorax and abdominal computed tomography scan with contrast. Multiple bone lesions of patients with primary tumor were accepted as metastasis. Multiple bone lesions of patients with multiple myeloma were accepted as multiple myeloma involvement. Histogram analysis was performed from lytic bone metastases and bone involvement of multiple myeloma. Results of both groups were compared.
In histogram analysis, minimum, median, and maximum gray level parameters were found to be significantly higher in lytic bone metastases (P < 0.001).
Computed tomography histogram analysis can be considered as a method to be used in the differentiation of multiple myeloma and lytic bone metastases.
转移瘤和多发性骨髓瘤是常见的恶性骨髓病变。由于影像学表现相似，可能难以区分。本研究的目的是确定计算机断层扫描成像上直方图分析的价值。
本研究纳入了23例原发性肿瘤患者和23例多发性骨髓瘤患者。所有患者在胸部和腹部计算机断层扫描增强扫描上均有溶骨性骨病变。原发性肿瘤患者的多发骨病变被视为转移瘤。多发性骨髓瘤患者的多发骨病变被视为多发性骨髓瘤累及。对溶骨性骨转移瘤和多发性骨髓瘤的骨受累情况进行直方图分析。比较两组结果。
在直方图分析中，发现溶骨性骨转移瘤的最小、中位数和最大灰度参数显著更高（P < 0.001）。
计算机断层扫描直方图分析可被视为用于区分多发性骨髓瘤和溶骨性骨转移瘤的一种方法。
